Joint response to GISAID regarding termination of SARS-CoV-2 data feeds

Trevor Bedford, Richard Neher and the Nextstrain team

Since our Nov 6 update, we haven't had further correspondence with GISAID Secretariat and the GISAID data feed for SARS-CoV-2 hasn't been updated. We believe it's likely safe to assume that the feed won't be returning and so our GISAID-based analyses at nextstrain.org.ncov/gisaid will remain on hold indefinitely with a last update on Oct 1, 2025. Meanwhile, we continue to update the open analyses based on GenBank / INSDC data weekly to produce phylogenetic analyses at nextstrain.org.ncov/open as well as variant fitness analyses at nextstrain.org/sars-cov-2/forecasts.

Meanwhile, on Jan 20, GISAID posted a statement that obliquely refers to Trevor Bedford as "individual four" and states that "GISAID terminated the data feed provided to a developer of software for visualizing phylogenomic data, after a review revealed that 'regional data packages' generated by the developer and offered through GISAID, were for the most part no longer being downloaded." As we described in detail in our Nov 6 blog post, we contend that making metadata and sequences available through the "nextregion" interface was a secondary byproduct enacted in May 2020 to allow reproducible research given strictures of GISAID's data resharing policy. We had previously documented emails from Jan 2020 and May 2020 that show this to be the case. This re-writing of history matches previous behavior by GISAID regarding their contentions surrounding the first publicly shared SARS-CoV-2 genome sequence.

COG-UK, outbreak.info and Cov-Spectrum were also referenced in GISAID's Jan 20 statement. Consequently, we, along with members of COG-UK, outbreak.info and Cov-Spectrum, have issued a joint response to GISAID that can be found at github.com/andersen-lab/2026_gisaid_response.

All source code is freely available under the terms of the GNU Affero General Public License. Screenshots may be used under a CC-BY-4.0 license and attribution to nextstrain.org must be provided.

This work is made possible by the open sharing of genetic data by research groups from all over the world. We gratefully acknowledge their contributions. Special thanks to Kristian Andersen, Josh Batson, David Blazes, Jesse Bloom, Peter Bogner, Anderson Brito, Matt Cotten, Ana Crisan, Tulio de Oliveira, Gytis Dudas, Vivien Dugan, Karl Erlandson, Nuno Faria, Jennifer Gardy, Nate Grubaugh, Becky Kondor, Dylan George, Ian Goodfellow, Betz Halloran, Christian Happi, Jeff Joy, Paul Kellam, Philippe Lemey, Nick Loman, Duncan MacCannell, Erick Matsen, Sebastian Maurer-Stroh, Placide Mbala, Danny Park, Oliver Pybus, Andrew Rambaut, Colin Russell, Pardis Sabeti, Katherine Siddle, Kristof Theys, Dave Wentworth, Shirlee Wohl and Cecile Viboud for comments, suggestions and data sharing.

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