{"version":"v2","meta":{"title":"SARS-CoV-2 phylogeny","updated":"2026-03-26","build_url":"https://github.com/neherlab/nextclade_data_workflows","maintainers":[{"name":"Cornelius Roemer","url":"https://neherlab.org"},{"name":"Richard Neher","url":"https://neherlab.org"}],"display_defaults":{"color_by":"clade_membership","distance_measure":"div","map_triplicate":false,"branch_label":"clade","transmission_lines":false},"genome_annotations":{"E":{"end":26472,"seqid":"profiles/clades/wuhan/reference_seq.gb","start":26245,"strand":"+","type":"CDS"},"M":{"end":27191,"seqid":"profiles/clades/wuhan/reference_seq.gb","start":26523,"strand":"+","type":"CDS"},"N":{"end":29533,"seqid":"profiles/clades/wuhan/reference_seq.gb","start":28274,"strand":"+","type":"CDS"},"ORF1a":{"end":13468,"seqid":"profiles/clades/wuhan/reference_seq.gb","start":266,"strand":"+","type":"CDS"},"ORF1b":{"end":21555,"seqid":"profiles/clades/wuhan/reference_seq.gb","start":13468,"strand":"+","type":"CDS"},"ORF3a":{"end":26220,"seqid":"profiles/clades/wuhan/reference_seq.gb","start":25393,"strand":"+","type":"CDS"},"ORF6":{"end":27387,"seqid":"profiles/clades/wuhan/reference_seq.gb","start":27202,"strand":"+","type":"CDS"},"ORF7a":{"end":27759,"seqid":"profiles/clades/wuhan/reference_seq.gb","start":27394,"strand":"+","type":"CDS"},"ORF7b":{"end":27887,"seqid":"profiles/clades/wuhan/reference_seq.gb","start":27756,"strand":"+","type":"CDS"},"ORF8":{"end":28259,"seqid":"profiles/clades/wuhan/reference_seq.gb","start":27894,"strand":"+","type":"CDS"},"ORF9b":{"end":28577,"seqid":"profiles/clades/wuhan/reference_seq.gb","start":28284,"strand":"+","type":"CDS"},"S":{"end":25384,"seqid":"profiles/clades/wuhan/reference_seq.gb","start":21563,"strand":"+","type":"CDS"},"nuc":{"end":29903,"start":1,"strand":"+","type":"source"}},"description":"This phylogeny shows evolutionary relationships of SARS-CoV-2 viruses from the ongoing novel coronavirus COVID-19 pandemic.\n\nAll data we use were deposited in GISAID by scientists around the world.\nWe gratefully acknowledge the authors, originating and submitting laboratories of the genetic sequence and metadata made available through [GISAID](https://gisaid.org) on which this research is based. A full listing of all originating and submitting laboratories is available below. An attribution table is available by clicking on \"Download Data\" at the bottom of the page and then clicking on \"Strain Metadata\" in the resulting dialog box.\n","colorings":[{"key":"clade_membership","title":"Clade","type":"categorical","scale":[["23I","#5E1D9D"],["24A","#482BB6"],["24B","#3F45C8"],["24C","#3F62D0"],["24D","#447DCC"],["24E","#4D92BF"],["24F","#58A2AC"],["24G","#66AE96"],["24H","#76B680"],["24I","#89BB6B"],["25A","#9DBE5A"],["25B","#B2BD4D"],["25C","#C5B945"],["25D","#D5B03F"],["25E","#E1A13A"],["25F","#E68B35"],["25G","#E56E30"],["25H","#E04B29"],["25I","#DB2823"]]},{"key":"gt","title":"Genotype","type":"categorical"},{"key":"designation_date","title":"Designation 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L24-, P25-, P26-, A27S, I29T, I33T, Y49H, I51T, I63T, Y66H, I73T, I76T, V83A, I95T, I108T, I109T, I114T, I124T, G142D, Y144-, Y146Q, F157L, I167T, N185D, Y207H, I208T, I210V, I212L, I236T, I240T, Y245H, I250T, G257S, I259T, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I333T, G339H, I345T, S373P, T376A, I385T, I393T, D405N, I415T, K417N, I430T, N440K, K444T, G446S, L452R, L455F, F456L, N460K, I470T, T478K, E484A, F486S, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681H, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, L858I, I859T, I866T, I874T, I881T, I883T, I887T, I912T, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, I1105T, I1116T, I1117T, I1120T, I1136T, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*"}}},{"name":"XCN","node_attrs":{"div":116,"Nextclade_pango":{"value":"XCN"},"immune_escape":{"value":"1.3709381401972789"},"qc.frameShifts.totalFrameShifts":{"value":0},"clade_who":{"value":"recombinant"},"clade_display":{"value":"recombinant"},"ace2_binding":{"value":"0.18525999999999987"},"qc.stopCodons.totalStopCodons":{"value":0},"qc.overallScore":{"value":0},"totalAminoacidDeletions":{"value":12},"designation_recency":{"value":">8 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T9I, T11A; M: Q19E, A63T; N: P13L, E31-, R32-, S33-, R203K, G204R, S413R; ORF1a: Y13H, Y45H, Y81H, Y83H, Y110H, Y134H, S135R, Y165H, Y234H, Y236H, L293F, Y325H, Y374H, Y382H, Y388H, Y417H, Y435H, A474V, Y712H, T842I, Y919H, Y1067H, Y1108H, Y1113H, Y1116H, Y1141H, Y1160H, S1221L, Y1264H, G1307S, Y1381H, Y1455H, Y1500H, Y1545H, Y1580H, Y1610H, Y1613H, Y1636H, P1640S, Y1652H, Y1738H, Y1818H, Y1835H, Y1838H, Y1974H, Y1987H, Y1993H, Y2092H, Y2125H, Y2357H, Y2399H, Y2448H, Y2502H, Y2516H, Y2520H, Y2659H, Y2698H, Y2707H, Y2794H, Y2799H, Y2831H, V2862M, Y2883H, Y2986H, L3027F, Y3076H, T3090I, Y3125H, Y3152H, L3201F, Y3233H, T3255I, Y3304H, Y3327H, Y3343H, Y3395H, Y3426H, Y3427H, Y3435H, Y3509H, Y3580H, Y3581H, Y3631H, Y3633H, S3675-, G3676-, F3677-, K3821R, Y3895H, N4060S, Y4301H, Y4333H, Y4336H; ORF1b: P314L, G662S, R1315C, I1566V, T2163I; ORF3a: T223I; ORF6: L6D, L30D, L53D; ORF7a: S81L; ORF7b: L19F; ORF8: G8*; ORF9b: I5T, P10S, E27-, N28-, A29-; S: I20T, T21R, L24-, P25-, P26-, A27S, I29T, I33T, Y49H, I51T, I63T, Y66H, I73T, I76T, P82H, I95T, I108T, I109T, I114T, I124T, G142D, Y146H, K147E, W152R, F157L, I167T, K187E, Y207H, I208T, I210V, I212L, I236T, I240T, Y245H, I250T, G257S, I259T, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I333T, G339H, I345T, K356T, L368I, S373P, T376A, I385T, I393T, D405N, I415T, K417N, I430T, N440K, V445P, G446S, F456L, N460K, I470T, T478K, E484A, F486P, F490S, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, Y625H, I630T, P631S, I632T, I638T, I645T, I676T, I678T, N679K, P681H, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, I1105T, I1116T, I1117T, I1120T, I1136T, Y1159H, I1160T, I1231T, I1238T, Y1271H, 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T9I, T11A; M: Q19E, A63T; N: P13L, E31-, R32-, S33-, R203K, G204R, S413R; ORF1a: Y13H, Y45H, K47R, Y81H, Y83H, Y110H, Y134H, S135R, Y165H, Y234H, Y236H, S302F, Y325H, Y374H, Y382H, Y388H, Y417H, Y435H, Y712H, T842I, Y919H, Y1067H, Y1108H, Y1113H, Y1116H, Y1141H, Y1160H, Y1264H, G1307S, Y1381H, Y1455H, Y1500H, Y1545H, Y1580H, Y1610H, Y1613H, Y1636H, Y1652H, Y1738H, Y1818H, Y1835H, Y1838H, Y1974H, Y1987H, Y1993H, P2079Q, Y2092H, Y2125H, T2283I, Y2357H, Y2399H, Y2448H, Y2502H, Y2516H, Y2520H, Y2659H, Y2698H, Y2707H, Y2794H, Y2799H, Y2831H, Y2883H, Y2986H, L3027F, Y3076H, T3090I, Y3125H, Y3152H, L3201F, Y3233H, T3255I, Y3304H, Y3327H, Y3343H, Y3395H, Y3426H, Y3427H, Y3435H, Y3509H, Y3580H, Y3581H, Y3631H, Y3633H, S3675-, G3676-, F3677-, K3821R, Y3895H, P4220L, Y4301H, Y4333H, Y4336H; ORF1b: P314L, G662S, S959P, R1315C, I1566V, T2163I; ORF3a: T223I; ORF6: L6D, L30D, L53D; ORF7b: L19F; ORF8: G8*; ORF9b: I5T, P10S, E27-, N28-, A29-; S: I20T, T21R, L24-, P25-, P26-, A27S, I29T, I33T, Y49H, 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C1274*"}}},{"name":"XDJ","node_attrs":{"div":109,"Nextclade_pango":{"value":"XDJ"},"immune_escape":{"value":"1.1968892804259947"},"qc.frameShifts.totalFrameShifts":{"value":0},"clade_who":{"value":"recombinant"},"clade_display":{"value":"recombinant"},"ace2_binding":{"value":"-0.36673000000000006"},"qc.stopCodons.totalStopCodons":{"value":0},"qc.overallScore":{"value":0},"totalAminoacidDeletions":{"value":13},"designation_recency":{"value":">8 weeks"},"clade_membership":{"value":"recombinant"},"clade_nextstrain":{"value":"recombinant"},"totalAminoacidSubstitutions":{"value":72},"designation_date":{"value":"2023-12-17"},"partiallyAliased":{"value":"XDJ"},"placement_prior":{"value":-10}},"branch_attrs":{"mutations":{"nuc":["C241T","A405G","T670G","C2790T","C3037T","G4184A","C4321T","C8947T","C9344T","A9424G","C9534T","C9866T","C10029T","C10198T","G10447A","C10449A","A10861G","T11288-","C11289-","T11290-","G11291-","G11292-","T11293-","T11294-","T11295-","T11296-","C11750T","C11956T","A12397G","T12730A","C12880T","C14408T","A14856G","G15451A","C15714T","C15738T","T15939C","T16342C","A16878T","C17410T","T17859C","A18163G","A18492G","A19326G","C19955T","A20055G","C21618T","T21633-","A21634-","C21635-","C21636-","C21637-","C21638-","C21639-","T21640-","G21641-","G21718T","T21810C","G21987A","T21992-","A21993-","T21994-","C22000A","C22033A","C22109G","T22200A","G22317T","C22480T","G22577C","G22578A","G22599C","C22664A","C22674T","T22679C","C22686T","A22688G","G22775A","A22786C","G22813T","T22882G","G22895C","T22896C","G22898A","G22927T","T22930A","T22942G","G22992A","C22995A","A23013C","T23018C","T23019C","T23031C","A23055G","A23063T","T23075C","A23403G","C23525T","T23599G","C23604A","C23854A","G23948T","A24424T","T24469A","C25000T","C25416T","C25572T","C25584T","C26060T","C26270T","A26275G","C26577G","G26709A","C26858T","A27259C","G27382C","A27383T","T27384C","A27507C","C27807T","G27915T","A28271T","T28297C","C28311T","G28362-","A28363-","G28364-","A28365-","A28366-","C28367-","G28368-","C28369-","A28370-","G28881A","G28882A","G28883C","G29081T","A29510C","C29625T","A29700G","G29734-","A29735-","G29736-","G29737-","C29738-","C29739-","A29740-","C29741-","G29742-","C29743-","G29744-","G29745-","A29746-","G29747-","T29748-","A29749-","C29750-","G29751-","A29752-","T29753-","C29754-","G29755-","A29756-","G29757-","T29758-","G29759-"],"E":["T9I","T11A"],"M":["Q19E","A63T"],"N":["P13L","E31-","R32-","S33-","R203K","G204R","V270L","S413R"],"ORF1a":["Y13H","Y45H","K47R","Y81H","Y83H","Y110H","Y134H","S135R","Y165H","Y234H","Y236H","Y325H","Y374H","Y382H","Y388H","Y417H","Y435H","Y712H","T842I","Y919H","Y1067H","Y1108H","Y1113H","Y1116H","Y1141H","Y1160H","Y1264H","G1307S","Y1381H","Y1455H","Y1500H","Y1545H","Y1580H","Y1610H","Y1613H","Y1636H","Y1652H","Y1738H","Y1818H","Y1835H","Y1838H","Y1974H","Y1987H","Y1993H","Y2092H","Y2125H","Y2357H","Y2399H","Y2448H","Y2502H","Y2516H","Y2520H","Y2659H","Y2698H","Y2707H","Y2794H","Y2799H","Y2831H","Y2883H","Y2986H","L3027F","Y3076H","T3090I","Y3125H","Y3152H","L3201F","Y3233H","T3255I","Y3304H","Y3327H","Y3343H","Y3395H","Y3426H","Y3427H","Y3435H","Y3509H","Y3580H","Y3581H","Y3631H","Y3633H","S3675-","G3676-","F3677-","K3821R","L3829F","Y3895H","Y4301H","Y4333H","Y4336H"],"ORF1b":["P314L","G662S","S959P","R1315C","I1566V","T2163I"],"ORF3a":["T223I"],"ORF6":["L6D","L30D","L53D"],"ORF7b":["L19F"],"ORF8":["G8*"],"ORF9b":["I5T","P10S","E27-","N28-","A29-"],"S":["I20T","T21R","L24-","P25-","P26-","A27S","I29T","I33T","Y49H","I51T","Q52H","I63T","Y66H","I73T","I76T","V83A","I95T","I108T","I109T","I114T","I124T","G142D","Y144-","Y146Q","F157L","I167T","Q183E","Y207H","I208T","I212L","G213E","I236T","I240T","Y245H","I250T","G252V","I259T","I274T","I284T","I286T","I299T","I302T","I307T","I315T","I323T","I333T","G339H","I345T","L368I","S373P","T376A","I385T","I393T","D405N","I415T","K417N","I430T","N440K","V445P","G446S","L455F","F456L","N460K","I470T","T478K","E484A","F486P","F490S","Q498R","I500T","Y505H","Y519H","I523T","I531T","I547T","I549T","I553T","I572T","I573T","I581T","I588T","I599T","I602T","I604T","D614G","I618T","Y625H","I630T","I632T","I638T","I645T","I676T","I678T","N679K","P681H","I696T","I716T","I719T","I723T","I724T","I732T","I734T","I739T","I747T","I761T","N764K","I768T","I778T","I791T","D796Y","I827T","I859T","I866T","I874T","I881T","I883T","I887T","I912T","I941T","Q954H","I961T","N969K","I998T","I1006T","I1009T","I1027T","Y1048H","Y1058H","Y1064H","I1066T","I1076T","I1077T","Y1083H","Y1088H","I1100T","Y1101H","I1105T","I1116T","I1117T","I1120T","I1136T","Y1159H","I1160T","I1231T","I1238T","Y1271H","I1273T","C1274*"]},"labels":{"aa":"E: T9I, T11A; M: Q19E, A63T; N: P13L, E31-, R32-, S33-, R203K, G204R, V270L, S413R; ORF1a: Y13H, Y45H, K47R, Y81H, Y83H, Y110H, Y134H, S135R, Y165H, Y234H, Y236H, Y325H, Y374H, Y382H, Y388H, Y417H, Y435H, Y712H, T842I, Y919H, Y1067H, Y1108H, Y1113H, Y1116H, Y1141H, Y1160H, Y1264H, G1307S, Y1381H, Y1455H, Y1500H, Y1545H, Y1580H, Y1610H, Y1613H, Y1636H, Y1652H, Y1738H, Y1818H, Y1835H, Y1838H, Y1974H, Y1987H, Y1993H, Y2092H, Y2125H, Y2357H, Y2399H, Y2448H, Y2502H, Y2516H, Y2520H, Y2659H, Y2698H, Y2707H, Y2794H, Y2799H, Y2831H, Y2883H, Y2986H, L3027F, Y3076H, T3090I, Y3125H, Y3152H, L3201F, Y3233H, T3255I, Y3304H, Y3327H, Y3343H, Y3395H, Y3426H, Y3427H, Y3435H, Y3509H, Y3580H, Y3581H, Y3631H, Y3633H, S3675-, G3676-, F3677-, K3821R, L3829F, Y3895H, Y4301H, Y4333H, Y4336H; ORF1b: P314L, G662S, S959P, R1315C, I1566V, T2163I; ORF3a: T223I; ORF6: L6D, L30D, L53D; ORF7b: L19F; ORF8: G8*; ORF9b: I5T, P10S, E27-, N28-, A29-; S: I20T, T21R, L24-, P25-, P26-, A27S, I29T, I33T, Y49H, I51T, Q52H, I63T, Y66H, I73T, I76T, V83A, I95T, I108T, I109T, I114T, I124T, G142D, Y144-, Y146Q, F157L, I167T, Q183E, Y207H, I208T, I212L, G213E, I236T, I240T, Y245H, I250T, G252V, I259T, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I333T, G339H, I345T, L368I, S373P, T376A, I385T, I393T, D405N, I415T, K417N, I430T, N440K, V445P, G446S, L455F, F456L, N460K, I470T, T478K, E484A, F486P, F490S, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681H, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, I1105T, I1116T, I1117T, I1120T, I1136T, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*","spike_mutations":"I20T, 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N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, I1105T, I1116T, I1117T, I1120T, I1136T, P1143L, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*"}}},{"name":"XDW","node_attrs":{"div":115,"Nextclade_pango":{"value":"XDW"},"immune_escape":{"value":"1.450453001635465"},"qc.frameShifts.totalFrameShifts":{"value":0},"clade_who":{"value":"recombinant"},"clade_display":{"value":"recombinant"},"ace2_binding":{"value":"1.15919"},"qc.stopCodons.totalStopCodons":{"value":0},"qc.overallScore":{"value":0},"totalAminoacidDeletions":{"value":17},"designation_recency":{"value":">8 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T9I, T11A; M: Q19E, A63T; N: P13L, E31-, R32-, S33-, R203K, G204R, S413R; ORF1a: Y13H, Y45H, Y81H, Y83H, Y110H, Y134H, S135R, Y165H, A211D, Y234H, Y236H, Y325H, Y374H, Y382H, Y388H, Y417H, Y435H, Y621C, Y712H, T842I, Y919H, V1056L, Y1067H, Y1108H, Y1113H, Y1116H, Y1141H, Y1160H, Y1264H, G1307S, Y1381H, Y1455H, Y1500H, Y1545H, Y1580H, Y1610H, Y1613H, Y1636H, Y1652H, Y1738H, Y1818H, Y1835H, Y1838H, K1973R, Y1974H, Y1987H, Y1993H, Y2092H, Y2125H, Y2357H, Y2399H, Y2448H, Y2502H, Y2516H, Y2520H, N2526S, Y2659H, Y2698H, Y2707H, A2710T, Y2794H, Y2799H, Y2831H, Y2883H, Y2986H, L3027F, Y3076H, T3090I, Y3125H, Y3152H, Y3233H, T3255I, Y3304H, Y3327H, Y3343H, Y3395H, Y3426H, Y3427H, Y3435H, Y3509H, Y3580H, Y3581H, V3593F, Y3631H, Y3633H, S3675-, G3676-, F3677-, K3821R, Y3895H, T4175I, Y4301H, Y4333H, Y4336H; ORF1b: P218L, P314L, R1315C, I1566V, T2163I, P2612S; ORF3a: T223I; ORF6: L6D, L30D, L53D; ORF7b: L19F; ORF8: G8*; ORF9b: I5T, P10S, E27-, N28-, A29-, S63F; S: I20T, L24-, P25-, P26-, A27S, I29T, I33T, Y49H, S50L, I51T, I63T, Y66H, H69-, V70-, I73T, I76T, I95T, I108T, I109T, I114T, I124T, V127F, G142D, Y144-, Y146H, F157S, R158G, I167T, Y207H, I208T, N211-, L216F, I236T, I240T, Y245N, I250T, I259T, A263V, A264D, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I332V, I333T, G339H, I345T, K356T, S373P, T376A, I385T, I393T, R403K, D405N, I415T, K417N, I430T, N440K, V445H, G446S, N450D, L452W, N460K, I470T, T478K, N481K, V483-, E484K, F486P, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, E554K, A570V, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, P621S, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681H, I696T, A701V, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, I1105T, I1116T, 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T9I; M: D3H, Q19E, T30A, A63T, A104V; N: P13L, E31-, R32-, S33-, R203K, G204R, S413R; ORF1a: Y13H, Y45H, Y81H, Y83H, Y110H, Y134H, S135R, Y165H, A211D, Y234H, Y236H, Y325H, Y374H, Y382H, Y388H, Y417H, Y435H, Y712H, T842I, Y919H, V1056L, Y1067H, Y1108H, Y1113H, Y1116H, Y1141H, Y1160H, Y1264H, G1307S, Y1381H, Y1455H, Y1500H, D1513E, Y1545H, Y1580H, Y1610H, Y1613H, Y1636H, Y1652H, Y1738H, Y1818H, Y1835H, Y1838H, K1973R, Y1974H, Y1987H, Y1993H, Y2092H, Y2125H, Y2357H, Y2399H, Y2448H, Y2502H, Y2516H, Y2520H, N2526S, A2529S, Y2659H, Y2698H, Y2707H, A2710T, Y2794H, Y2799H, Y2831H, Y2883H, Y2986H, L3027F, Y3076H, T3090I, Y3125H, Y3152H, Y3233H, T3255I, Y3304H, Y3327H, Y3343H, Y3395H, Y3426H, Y3427H, Y3435H, Y3509H, Y3580H, Y3581H, V3593F, Y3631H, Y3633H, S3675-, G3676-, F3677-, Y3895H, T4175I, Y4301H, Y4333H, Y4336H; ORF1b: K82R, P314L, R1315C, I1566V, T2163I; ORF3a: T223I; ORF6: L6D, L30D, L53D; ORF7b: L19F; ORF8: G8*; ORF9b: I5T, P10S, E27-, N28-, A29-; S: I20T, L24-, P25-, P26-, A27S, I29T, I33T, Y49H, S50L, I51T, I63T, Y66H, H69-, V70-, I73T, I76T, I95T, I108T, I109T, I114T, I124T, V127F, G142D, Y144-, Y146H, F157S, R158G, I167T, Y207H, I208T, N211-, L216F, I236T, I240T, Y245N, I250T, I259T, A264D, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I332V, I333T, G339H, I345T, T346R, K356T, S373P, T376A, I385T, I393T, R403K, D405N, I415T, K417N, I430T, N440K, V445H, G446S, N450D, L452W, L455S, N460K, I470T, T478K, N481K, V483-, E484K, F486P, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, E554K, A570V, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, P621S, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681R, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, S939F, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, I1105T, I1116T, 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I1120T, I1136T, P1143L, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*","spike_mutations":"I20T, L24-, P25-, P26-, A27S, I29T, S31-, I33T, Y49H, S50L, I51T, I63T, Y66H, H69-, V70-, I73T, I76T, I95T, I108T, I109T, I114T, I124T, V127F, G142D, Y144-, Y146H, F157S, R158G, I167T, Y207H, I208T, N211-, L216F, I236T, I240T, Y245N, I250T, I259T, A264D, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I332V, I333T, G339H, I345T, T346R, K356T, S373P, T376A, I385T, I393T, R403K, D405N, I415T, K417N, I430T, N440K, V445H, G446S, N450D, L452W, F456V, N460K, I470T, T478K, N481K, V483-, E484K, F486P, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, E554K, A570V, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, P621S, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681R, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, S939F, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, I1105T, I1116T, I1117T, I1120T, I1136T, P1143L, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*"}}},{"name":"XEH","node_attrs":{"div":125,"Nextclade_pango":{"value":"XEH"},"immune_escape":{"value":"1.7206397516519647"},"qc.frameShifts.totalFrameShifts":{"value":0},"clade_who":{"value":"recombinant"},"clade_display":{"value":"recombinant"},"ace2_binding":{"value":"-1.04211"},"qc.stopCodons.totalStopCodons":{"value":0},"qc.overallScore":{"value":0},"totalAminoacidDeletions":{"value":18},"designation_recency":{"value":">8 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T9I; M: D3H, Q19E, T30A, A63T, A104V; N: P13L, E31-, R32-, S33-, R203K, G204R, Q229K, S413L; ORF1a: Y13H, Y45H, Y81H, Y83H, Y110H, Y134H, S135R, Y165H, A211D, Y234H, Y236H, Y325H, Y374H, Y382H, Y388H, Y417H, Y435H, Y712H, T842I, Y919H, V1056L, Y1067H, Y1108H, Y1113H, Y1116H, Y1141H, Y1160H, Y1264H, G1307S, Y1381H, Y1455H, Y1500H, Y1545H, Y1580H, Y1610H, Y1613H, Y1636H, Y1652H, Y1738H, Y1818H, Y1835H, Y1838H, K1973R, Y1974H, Y1987H, Y1993H, Y2092H, Y2125H, T2283I, Y2357H, Y2399H, Y2448H, Y2502H, Y2516H, Y2520H, N2526S, Y2659H, Y2698H, Y2707H, A2710T, Y2794H, Y2799H, Y2831H, Y2883H, Y2986H, L3027F, Y3076H, T3090I, Y3125H, Y3152H, Y3233H, T3255I, Y3304H, Y3327H, Y3343H, Y3395H, Y3426H, Y3427H, Y3435H, Y3509H, Y3580H, Y3581H, V3593F, Y3631H, Y3633H, S3675-, G3676-, F3677-, Y3895H, T4175I, Y4301H, Y4333H, Y4336H; ORF1b: P314L, R1315C, I1566V, T2163I; ORF3a: T223I; ORF6: L6D, L30D, L53D, L61I; ORF9b: P10S, E27-, N28-, A29-; S: I20T, L24-, P25-, P26-, A27S, I29T, S31-, I33T, Y49H, S50L, I51T, I63T, Y66H, H69-, V70-, I73T, I76T, I95T, I108T, I109T, I114T, I124T, V127F, G142D, Y144-, Y146H, F157S, R158G, I167T, Y207H, I208T, N211-, L216F, I236T, I240T, Y245N, I250T, I259T, A264D, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I332V, I333T, G339H, I345T, K356T, S373P, T376A, I385T, I393T, R403K, D405N, I415T, K417N, I430T, N440K, V445H, G446S, N450D, L452W, L455S, F456L, N460K, I470T, T478K, N481K, V483-, E484K, F486P, Q493E, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, E554K, A570V, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, P621S, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681R, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, S939F, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, V1104L, I1105T, I1116T, I1117T, 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V1104L, I1105T, I1116T, I1117T, I1120T, I1136T, P1143L, Y1159H, I1160T, I1231T, I1238T, V1264L, Y1271H, I1273T, C1274*","spike_mutations":"I20T, L24-, P25-, P26-, A27S, I29T, S31-, I33T, Y49H, S50L, I51T, I63T, Y66H, H69-, V70-, I73T, I76T, I95T, I108T, I109T, I114T, I124T, V127F, G142D, Y144-, Y146H, F157S, R158G, I167T, Y207H, I208T, N211-, L216F, I236T, I240T, Y245N, I250T, I259T, A264D, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I332V, I333T, G339H, I345T, T346R, K356T, S373P, T376A, I385T, I393T, R403K, D405N, I415T, K417N, I430T, N440K, V445H, G446S, N450D, L452W, L455S, F456L, N460K, I470T, T478K, N481K, V483-, E484K, F486P, Q493E, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, E554K, A570V, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, P621S, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681R, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, S939F, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, V1104L, I1105T, I1116T, I1117T, I1120T, I1136T, P1143L, Y1159H, I1160T, I1231T, I1238T, V1264L, Y1271H, I1273T, C1274*"}}},{"name":"XEU","node_attrs":{"div":130,"Nextclade_pango":{"value":"XEU"},"immune_escape":{"value":"1.5260901910056954"},"qc.frameShifts.totalFrameShifts":{"value":0},"clade_who":{"value":"recombinant"},"clade_display":{"value":"recombinant"},"ace2_binding":{"value":"-1.15353"},"qc.stopCodons.totalStopCodons":{"value":0},"qc.overallScore":{"value":0},"totalAminoacidDeletions":{"value":17},"designation_recency":{"value":">8 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T9I; M: D3H, Q19E, T30A, A63T, A104V; N: P13L, E31-, R32-, S33-, R203K, G204P, Q229K, S413R; ORF1a: Y13H, Y45H, Y81H, Y83H, Y134H, S135R, Y165H, A211D, Y234H, Y236H, Y325H, Y374H, Y382H, Y388H, Y417H, Y435H, Y712H, T842I, Y919H, V1056L, Y1067H, Y1108H, Y1113H, Y1116H, Y1141H, Y1160H, Y1264H, G1307S, Y1381H, Y1455H, Y1500H, Y1545H, Y1580H, Y1610H, Y1613H, Y1636H, Y1652H, Y1738H, Y1818H, Y1835H, Y1838H, K1973R, Y1974H, Y1987H, Y1993H, Y2092H, Y2125H, Y2357H, Y2399H, Y2448H, Y2502H, Y2516H, Y2520H, N2526S, Y2659H, Y2698H, Y2707H, A2710T, Y2794H, Y2799H, Y2831H, Y2883H, Y2986H, L3027F, Y3076H, T3090I, Y3125H, Y3152H, Y3233H, T3255I, Y3304H, Y3327H, Y3343H, Y3395H, Y3426H, Y3427H, Y3435H, Y3509H, Y3580H, Y3581H, V3593F, Y3631H, Y3633H, S3675-, G3676-, F3677-, Y3895H, T4175I, Y4301H, Y4333H, Y4336H; ORF1b: P314L, R1315C, I1566V, T2163I; ORF3a: T223I; ORF6: L6D, L30D, L53D; ORF9b: P10S, E27-, N28-, A29-; S: I20T, T22N, L24-, P25-, P26-, A27S, I29T, I33T, Y49H, S50L, I51T, F59S, I63T, Y66H, H69-, V70-, I73T, I76T, I95T, I108T, I109T, I114T, I124T, V127F, G142D, Y144-, Y146H, F157S, R158G, I167T, Y207H, I208T, N211-, L216F, I236T, I240T, Y245N, I250T, I259T, A264D, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I332V, I333T, G339H, I345T, T346R, K356T, S373P, T376A, I385T, I393T, R403K, D405N, I415T, K417N, I430T, N440K, V445H, G446S, N450D, L452W, L455S, F456L, N460K, I470T, T478K, N481K, V483-, E484K, F486P, Q493E, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, E554K, A570V, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, P621S, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681R, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, S939F, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, V1104L, I1105T, I1116T, I1117T, I1120T, 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I1105T, I1116T, I1117T, I1120T, I1136T, P1143L, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*","spike_mutations":"I20T, T22N, L24-, P25-, P26-, A27S, I29T, I33T, Y49H, S50L, I51T, F59S, I63T, Y66H, H69-, V70-, I73T, I76T, I95T, I108T, I109T, I114T, I124T, V127F, G142D, Y144-, Y146H, F157S, R158G, I167T, Y207H, I208T, N211-, L216F, I236T, I240T, Y245N, I250T, I259T, A264D, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I332V, I333T, G339H, I345T, T346R, K356T, S373P, T376A, I385T, I393T, R403K, D405N, I415T, K417N, I430T, N440K, V445H, G446S, N450D, L452W, L455S, F456L, N460K, I470T, T478K, N481K, V483-, E484K, F486P, Q493E, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, E554K, A570V, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, P621S, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681R, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, S939F, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, V1104L, I1105T, I1116T, I1117T, I1120T, I1136T, P1143L, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*"}}},{"name":"XF","node_attrs":{"div":57,"Nextclade_pango":{"value":"XF"},"qc.frameShifts.totalFrameShifts":{"value":0},"clade_who":{"value":"recombinant"},"clade_display":{"value":"recombinant"},"qc.stopCodons.totalStopCodons":{"value":0},"qc.overallScore":{"value":0},"totalAminoacidDeletions":{"value":16},"designation_recency":{"value":">8 weeks"},"clade_membership":{"value":"recombinant"},"clade_nextstrain":{"value":"recombinant"},"totalAminoacidSubstitutions":{"value":47},"designation_date":{"value":"2022-03-16"},"partiallyAliased":{"value":"XF"},"placement_prior":{"value":-5.13496732711792}},"branch_attrs":{"mutations":{"nuc":["G210T","C241T","T1390C","A2255G","C3037T","G4181T","G6513-","T6514-","T6515-","G8393A","C10029T","C10449A","T11285-","T11286-","G11287-","T11288-","C11289-","T11290-","G11291-","G11292-","T11293-","A11537G","T13195C","C14408T","C15240T","A18163G","C21762T","T21765-","A21766-","C21767-","A21768-","T21769-","G21770-","C21846T","G21987-","T21988-","G21989-","T21990-","T21991-","T21992-","A21993-","T21994-","T21995-","A22194-","T22195-","T22196-","G22578A","T22673C","C22674T","T22679C","C22686T","G22813T","T22882G","G22898A","G22992A","C22995A","A23013C","A23040G","G23048A","A23055G","A23063T","T23075C","C23202A","A23403G","C23525T","T23599G","C23604A","C23854A","G23948T","C24130A","A24424T","T24469A","C24503T","C25000T","C25584T","C26270T","A26530G","C26577G","G26709A","A27259C","C27807T","A28271T","C28311T","G28362-","A28363-","G28364-","A28365-","A28366-","C28367-","G28368-","C28369-","A28370-","G28881A","G28882A","G28883C","C29632T"],"E":["T9I"],"M":["D3G","Q19E","A63T"],"N":["P13L","E31-","R32-","S33-","R203K","G204R"],"ORF1a":["Y13H","Y45H","Y81H","Y83H","Y110H","Y134H","Y165H","Y234H","Y236H","Y325H","Y374H","Y382H","Y388H","Y417H","Y435H","I664V","Y712H","Y919H","Y1067H","Y1108H","Y1113H","Y1116H","Y1141H","Y1160H","Y1264H","A1306S","Y1381H","Y1455H","Y1500H","Y1545H","Y1580H","Y1610H","Y1613H","Y1636H","Y1652H","Y1738H","Y1818H","Y1835H","Y1838H","Y1974H","Y1987H","Y1993H","S2083-","L2084I","Y2092H","Y2125H","Y2357H","Y2399H","Y2448H","Y2502H","Y2516H","Y2520H","Y2659H","Y2698H","Y2707H","A2710T","Y2794H","Y2799H","Y2831H","Y2883H","Y2986H","Y3076H","Y3125H","Y3152H","Y3233H","T3255I","Y3304H","Y3327H","Y3343H","Y3395H","Y3426H","Y3427H","Y3435H","Y3509H","Y3580H","Y3581H","Y3631H","Y3633H","L3674-","S3675-","G3676-","I3758V","K3821R","Y3895H","Y4301H","Y4333H","Y4336H"],"ORF1b":["P314L","I1566V"],"ORF6":["L6D","L30D","L53D","L61D"],"ORF7b":["L19F"],"ORF9b":["P10S","E27-","N28-","A29-"],"S":["I19T","I20T","T21R","I29T","I33T","Y49H","I51T","I63T","Y66H","A67V","H69-","V70-","I73T","I76T","I108T","I109T","I114T","I124T","G142-","V143-","Y144-","Y145D","Y146H","I167T","Y207H","I208T","N211-","G213V","I236T","I240T","Y245H","I250T","I259T","I274T","I284T","I286T","I299T","I302T","I307T","I315T","I323T","I333T","G339D","I345T","T346R","F371L","S373P","I385T","I393T","S408R","I415T","K417N","I430T","N440K","G446S","I470T","T478K","E484A","Q493R","G496S","Q498R","I500T","Y505H","Y519H","I523T","I531T","I547K","I549T","I553T","I572T","I573T","I581T","I588T","I599T","I602T","I604T","D614G","I618T","Y625H","I630T","I632T","I638T","I645T","I676T","I678T","N679K","P681H","I696T","I716T","I719T","I723T","I724T","I732T","I734T","I739T","I747T","I761T","N764K","I768T","I778T","I791T","D796Y","I827T","N856K","I859T","I866T","I874T","I881T","I883T","I887T","I912T","I941T","Q954H","I961T","N969K","L981F","I998T","I1006T","I1009T","I1027T","Y1048H","Y1058H","Y1064H","I1066T","I1076T","I1077T","Y1083H","Y1088H","I1100T","Y1101H","I1105T","I1116T","I1117T","I1120T","I1136T","Y1159H","I1160T","I1231T","I1238T","Y1271H","I1273T","C1274*"]},"labels":{"aa":"E: T9I; M: D3G, Q19E, A63T; N: P13L, E31-, R32-, S33-, R203K, G204R; ORF1a: Y13H, Y45H, Y81H, Y83H, Y110H, Y134H, Y165H, Y234H, Y236H, Y325H, Y374H, Y382H, Y388H, Y417H, Y435H, I664V, Y712H, Y919H, Y1067H, Y1108H, Y1113H, Y1116H, Y1141H, Y1160H, Y1264H, A1306S, Y1381H, Y1455H, Y1500H, Y1545H, Y1580H, Y1610H, Y1613H, Y1636H, Y1652H, Y1738H, Y1818H, Y1835H, Y1838H, Y1974H, Y1987H, Y1993H, S2083-, L2084I, Y2092H, Y2125H, Y2357H, Y2399H, Y2448H, Y2502H, Y2516H, Y2520H, Y2659H, Y2698H, Y2707H, A2710T, Y2794H, Y2799H, Y2831H, Y2883H, Y2986H, Y3076H, Y3125H, Y3152H, Y3233H, T3255I, Y3304H, Y3327H, Y3343H, Y3395H, Y3426H, Y3427H, Y3435H, Y3509H, Y3580H, Y3581H, Y3631H, Y3633H, L3674-, S3675-, G3676-, I3758V, K3821R, Y3895H, Y4301H, Y4333H, Y4336H; ORF1b: P314L, I1566V; ORF6: L6D, L30D, L53D, L61D; ORF7b: L19F; ORF9b: P10S, E27-, N28-, A29-; S: I19T, I20T, T21R, I29T, I33T, Y49H, I51T, I63T, Y66H, A67V, H69-, V70-, I73T, I76T, I108T, I109T, I114T, I124T, G142-, V143-, Y144-, Y145D, Y146H, I167T, Y207H, I208T, N211-, G213V, I236T, I240T, Y245H, I250T, I259T, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I333T, G339D, I345T, T346R, F371L, S373P, I385T, I393T, S408R, I415T, K417N, I430T, N440K, G446S, I470T, T478K, E484A, Q493R, G496S, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547K, I549T, I553T, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681H, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, N856K, I859T, I866T, I874T, I881T, I883T, I887T, I912T, I941T, Q954H, I961T, N969K, L981F, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, I1105T, I1116T, I1117T, I1120T, I1136T, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*","spike_mutations":"I19T, I20T, T21R, I29T, I33T, Y49H, I51T, I63T, Y66H, A67V, H69-, V70-, I73T, I76T, I108T, I109T, I114T, I124T, G142-, V143-, 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Y1101H, I1105T, I1116T, I1117T, I1120T, I1136T, P1143L, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*","spike_mutations":"I20T, T22N, L24-, P25-, P26-, A27S, I29T, S31P, I33T, Y49H, S50L, I51T, I63T, Y66H, H69-, V70-, I73T, I76T, I95T, I108T, I109T, I114T, I124T, V127F, G142D, Y144-, Y146H, F157S, R158G, I167T, K182R, R190S, Y207H, I208T, N211-, L216F, I236T, I240T, Y245N, I250T, I259T, A264D, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I332V, I333T, G339H, I345T, K356T, S373P, T376A, I385T, I393T, R403K, D405N, I415T, K417N, I430T, N440K, L441R, V445P, G446S, N450D, L452W, L455S, F456L, N460K, I470T, A475V, T478K, N481K, V483-, E484K, F486P, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, E554K, A570V, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, P621S, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681R, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791A, D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, S939F, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, I1105T, I1116T, I1117T, I1120T, I1136T, P1143L, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*"}}},{"name":"XFL","node_attrs":{"div":135,"Nextclade_pango":{"value":"XFL"},"immune_escape":{"value":"1.5260901910056954"},"qc.frameShifts.totalFrameShifts":{"value":0},"clade_who":{"value":"recombinant"},"clade_display":{"value":"recombinant"},"ace2_binding":{"value":"-1.15353"},"qc.stopCodons.totalStopCodons":{"value":0},"qc.overallScore":{"value":0},"totalAminoacidDeletions":{"value":17},"designation_recency":{"value":">8 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T9I; M: D3H, Q19E, T30A, A63T, A104V; N: P13L, E31-, R32-, S33-, R203K, G204P, Q229K, S413R; ORF1a: Y13H, Y45H, Y81H, Y83H, Y134H, S135R, Y165H, A211D, Y234H, Y236H, Y325H, Y374H, Y382H, Y388H, Y417H, Y435H, Y712H, T842I, Y919H, V1056L, Y1067H, Y1108H, Y1113H, Y1116H, Y1141H, Y1160H, Y1264H, G1307S, Y1381H, Y1455H, Y1500H, Y1545H, Y1580H, Y1610H, Y1613H, Y1636H, Y1652H, Y1738H, Q1757L, Y1818H, Y1835H, Y1838H, K1973R, Y1974H, Y1987H, Y1993H, Y2092H, Y2125H, Y2357H, Y2399H, Y2448H, Y2502H, Y2516H, Y2520H, N2526S, Y2659H, Y2698H, Y2707H, A2710T, Y2794H, Y2799H, Y2831H, Y2883H, Y2986H, L3027F, Y3076H, T3090I, Y3125H, Y3152H, Y3233H, T3255I, Y3304H, Y3327H, Y3343H, Y3395H, Y3426H, Y3427H, Y3435H, Y3509H, Y3580H, Y3581H, V3593F, Y3631H, Y3633H, S3675-, G3676-, F3677-, Y3895H, T4175I, Y4301H, Y4333H, Y4336H; ORF1b: P314L, R1315C, I1566V, T2163I; ORF3a: T223I; ORF6: L6D, L30D, L53D; ORF9b: P3H, P10S, E27-, N28-, A29-, R32L; S: I20T, T22N, L24-, P25-, P26-, A27S, I29T, I33T, Y49H, S50L, I51T, 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D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, S939F, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, D1084G, Y1088H, I1100T, Y1101H, I1105T, I1116T, I1117T, I1120T, I1136T, P1143L, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*"}}},{"name":"XFU","node_attrs":{"div":141,"Nextclade_pango":{"value":"XFU"},"immune_escape":{"value":"1.7892230544178447"},"qc.frameShifts.totalFrameShifts":{"value":0},"clade_who":{"value":"recombinant"},"clade_display":{"value":"recombinant"},"ace2_binding":{"value":"-1.10783"},"qc.stopCodons.totalStopCodons":{"value":0},"qc.overallScore":{"value":0},"totalAminoacidDeletions":{"value":17},"designation_recency":{"value":">8 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Y49H, S50L, I51T, I63T, Y66H, H69-, V70-, I73T, I76T, I95T, I108T, I109T, I114T, I124T, V127F, G142D, Y144-, Y146H, F157S, R158G, I167T, K182R, R190S, Y207H, I208T, N211-, L216F, I236T, I240T, Y245N, I250T, I259T, A264D, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I332V, I333T, G339H, I345T, K356T, S373P, T376A, I385T, I393T, R403K, D405N, I415T, K417N, I430T, N440K, L441R, V445P, G446S, N450D, L452W, L455S, F456L, N460K, I470T, T478K, N481K, V483-, E484K, F486P, Q493E, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, E554K, A570V, I572T, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, P621S, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681R, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, S939F, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, 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I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, S939F, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, I1105T, I1116T, I1117T, I1120T, I1136T, P1143L, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*"}}},{"name":"XGC","node_attrs":{"div":147,"Nextclade_pango":{"value":"XGC"},"immune_escape":{"value":"1.8842694951333954"},"qc.frameShifts.totalFrameShifts":{"value":0},"clade_who":{"value":"recombinant"},"clade_display":{"value":"recombinant"},"ace2_binding":{"value":"-2.6519399999999997"},"qc.stopCodons.totalStopCodons":{"value":0},"qc.overallScore":{"value":0},"totalAminoacidDeletions":{"value":17},"designation_recency":{"value":">8 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I29T, S31P, I33T, Y49H, S50L, I51T, I63T, Y66H, H69-, V70-, I73T, I76T, I95T, I108T, I109T, I114T, I124T, V127F, G142D, Y144-, Y146H, F157S, R158G, I167T, K182R, R190S, Y207H, I208T, N211-, L216F, I236T, I240T, Y245N, I250T, G257V, I259T, A264D, I274T, I284T, I286T, I299T, I302T, I307T, I315T, I323T, I332V, I333T, G339H, I345T, K356T, S373P, T376A, I385T, I393T, R403K, D405N, I415T, K417N, I430T, N440K, K444R, V445R, G446S, N450D, L452W, L455S, F456L, N460K, I470T, T478K, N481K, V483-, E484K, F486P, N487D, Q493E, Q498R, I500T, Y505H, Y519H, I523T, I531T, I547T, I549T, I553T, E554K, A570V, I573T, I581T, I588T, I599T, I602T, I604T, D614G, I618T, P621S, Y625H, I630T, I632T, I638T, I645T, I676T, I678T, N679K, P681R, I696T, I716T, I719T, I723T, I724T, I732T, I734T, I739T, I747T, I761T, N764K, I768T, I778T, I791T, D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, S939F, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, 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D796Y, I827T, I859T, I866T, I874T, I881T, I883T, I887T, I912T, S939F, I941T, Q954H, I961T, N969K, I998T, I1006T, I1009T, I1027T, Y1048H, Y1058H, Y1064H, I1066T, I1076T, I1077T, Y1083H, Y1088H, I1100T, Y1101H, I1105T, I1116T, I1117T, I1120T, I1136T, P1143L, Y1159H, I1160T, I1231T, I1238T, Y1271H, I1273T, C1274*"}}},{"name":"XGM","node_attrs":{"div":141,"Nextclade_pango":{"value":"XGM"},"immune_escape":{"value":"1.7206397516519647"},"qc.frameShifts.totalFrameShifts":{"value":0},"clade_who":{"value":"recombinant"},"clade_display":{"value":"recombinant"},"ace2_binding":{"value":"-1.11924"},"qc.stopCodons.totalStopCodons":{"value":0},"qc.overallScore":{"value":0},"totalAminoacidDeletions":{"value":17},"designation_recency":{"value":">8 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T9I; M: D3H, Q19E, T30A, A63T, A104V; N: P13L, E31-, R32-, S33-, R203K, G204R, Q229K, S413R; ORF1a: Y13H, Y45H, Y81H, Y83H, Y110H, Y134H, S135R, Y165H, A211D, Y234H, Y236H, Y325H, Y374H, Y382H, Y388H, Y417H, Y435H, Y712H, T842I, Y919H, V1056L, Y1067H, Y1108H, Y1113H, Y1116H, Y1141H, Y1160H, Y1264H, G1307S, Y1381H, T1401I, Y1455H, Y1500H, T1543I, Y1545H, Y1580H, Y1610H, Y1613H, Y1636H, Y1652H, Y1738H, Y1818H, Y1835H, Y1838H, K1973R, Y1974H, Y1987H, Y1993H, A1997V, Y2092H, Y2125H, T2283I, Y2357H, Y2399H, Y2448H, Y2502H, Y2516H, Y2520H, N2526S, S2535L, Y2659H, Y2698H, Y2707H, A2710T, Y2794H, Y2799H, Y2831H, Y2883H, Y2986H, L3027F, Y3076H, T3090I, Y3125H, Y3152H, Y3233H, T3255I, Y3304H, Y3327H, Y3343H, Y3395H, Y3426H, Y3427H, Y3435H, Y3509H, Y3580H, Y3581H, V3593F, Y3631H, Y3633H, S3675-, G3676-, F3677-, Y3895H, T4175I, Y4301H, Y4333H, Y4336H; ORF1b: P314L, R1315C, I1566V, T2163I; ORF3a: P178L, T223I; ORF6: L6D, L30D, L53D; ORF9b: P10S, E27-, N28-, A29-; S: I20T, T22N, L24-, P25-, P26-, 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D1168N","spike_mutations":"D1168N"}}}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]},"root_sequence":{"E":"MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNIVNVSLVKPSFYVYSRVKNLNSSRVPDLLV*","M":"MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNRFLYIIKLIFLWLLWPVTLACFVLAAVYRINWITGGIAIAMACLVGLMWLSYFIASFRLFARTRSMWSFNPETNILLNVPLHGTILTRPLLESELVIGAVILRGHLRIAGHHLGRCDIKDLPKEITVATSRTLSYYKLGASQRVAGDSGFAAYSRYRIGNYKLNTDHSSSSDNIALLVQ*","N":"MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQGLPNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSPDDQIGYYRRATRRIRGGDGKMKDLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNPANNAAIVLQLPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPGSSRGTSPARMAGNGGDAALALLLLDRLNQLESKMSGKGQQQQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGRRGPEQTQGNFGDQELIRQGTDYKHWPQIAQFAPSASAFFGMSRIGMEVTPSGTWLTYTGAIKLDDKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTVTLLPAADLDDFSKQLQQSMSSADSTQA*","ORF1a":"MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQHLKDGTCGLVEVEKGVLPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGETLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQENWNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQLDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFPLNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTGDFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESGLKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNLLEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGNFKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAAITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKLKPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLVNKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEIIFLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEKYCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEKCSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEFKLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPEEEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIAEIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGNLHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKVPTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREMLAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLINTLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSSKTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVITFDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPHNSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIKWADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELGDVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQIPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSKETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYYKKDNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVTFFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWSTKPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGDIILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNSVPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRIKASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTAALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLETIQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWLMWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVECTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRPINPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPINVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVNTFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVECLKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALIWNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWLKQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFANKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLPRVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVAYESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSGRWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCLAYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTNDVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFEEAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHLAKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHWLLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFLLPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTARTVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLARGIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYLVSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVLLSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKLCEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAKSEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALNNIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDADSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTACTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTPKGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSADAQSFLN","ORF1b":"RVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKDEDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQRLTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYANLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVVDSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQTYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRELGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQTVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDIRQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQDALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAATRGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLARKHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQAVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMMILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCSQHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKHPNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTVLQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCDVTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDWTNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKPRPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSHTVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGKSHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKFKVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQLPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLKAHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNAVASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSDRDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKTEGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEGCHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIPLMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCLCDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNAHVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADKFPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCLFWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQLPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYNMMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNTVYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDYKRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEGSVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFKPRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESPFELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKVTIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGDSATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLPTGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEGFFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFLIGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKEGQINDMILSLLSKGRLIIRENNRVVISSDVLVNN*","ORF3a":"MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFGWLIVGVALLAVFQSASKIITLKKRWQLALSKGVHFVCNLLLLFVTVYSHLLLVAAGLEAPFLYLYALVYFLQSINFVRIIMRLWLCWKCRSKNPLLYDANYFLCWHTNCYDYCIPYNSVTSSIVITSGDGTTSPISEHDYQIGGYTEKWESGVKDCVVLHSYFTSDYYQLYSTQLSTDTGVEHVTFFIYNKIVDEPEEHVQIHTIDGSSGVVNPVMEPIYDEPTTTTSVPL*","ORF6":"MFHLVDFQVTIAEILLIIMRTFKVSIWNLDYIINLIIKNLSKSLTENKYSQLDEEQPMEID*","ORF7a":"MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNSPFHPLADNKFALTCFSTQFAFACPDGVKHVYQLRARSVSPKLFIRQEEVQELYSPIFLIVAAIVFITLCFTLKRKTE*","ORF7b":"MIELSLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDHNETCHA*","ORF8":"MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSKWYIRVGARKSAPLIELCVDEAGSKSPIQYIDIGNYTVSCLPFTINCQEPKLGSLVVRCSFYEDFLEYHDVRVVLDFI*","ORF9b":"MDPKISEMHPALRLVDPQIQLAVTRMENAVGRDQNNVGPKVYPIILRLGSPLSLNMARKTLNSLEDKAFQLTPIAVQMTKLATTEELPDEFVVVTVK*","S":"MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSEPVLKGVKLHYT*","nuc":"ATTAAAGGTTTATACCTTCCCAGGTAACAAACCAACCAACTTTCGATCTCTTGTAGATCTGTTCTCTAAACGAACTTTAAAATCTGTGTGGCTGTCACTCGGCTGCATGCTTAGTGCACTCACGCAGTATAATTAATAACTAATTACTGTCGTTGACAGGACACGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAGCACATCTAGGTTTCGTCCGGGTGTGACCGAAAGGTAAGATGGAGAGCCTTGTCCCTGGTTTCAACGAGAAAACACACGTCCAACTCAGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGGAGACTCCGTGGAGGAGGTCTTATCAGAGGCACGTCAACATCTTAAAGATGGCACTTGTGGCTTAGTAGAAGTTGAAAAAGGCGTTTTGCCTCAACTTGAACAGCCCTATGTGTTCATCAAACGTTCGGATGCTCGAACTGCACCTCATGGTCATGTTATGGTTGAGCTGGTAGCAGAACTCGAAGGCATTCAGTACGGTCGTAGTGGTGAGACACTTGGTGTCCTTGTCCCTCATGTGGGCGAAATACCAGTGGCTTACCGCAAGGTTCTTCTTCGTAAGAACGGTAATAAAGGAGCTGGTGGCCATAGTTACGGCGCCGATCTAAAGTCATTTGACTTAGGCGACGAGCTTGGCACTGATCCTTATGAAGATTTTCAAGAAAACTGGAACACTAAACATAGCAGTGGTGTTACCCGTGAACTCATGCGTGAGCTTAACGGAGGGGCATACACTCGCTATGTCGATAACAACTTCTGTGGCCCTGATGGCTACCCTCTTGAGTGCATTAAAGACCTTCTAGCACGTGCTGGTAAAGCTTCATGCACTTTGTCCGAACAACTGGACTTTATTGACACTAAGAGGGGTGTATACTGCTGCCGTGAACATGAGCATGAAATTGCTTGGTACACGGAACGTTCTGAAAAGAGCTATGAATTGCAGACACCTTTTGAAATTAAATTGGCAAAGAAATTTGACACCTTCAATGGGGAATGTCCAAATTTTGTATTTCCCTTAAATTCCATAATCAAGACTATTCAACCAAGGGTTGAAAAGAAAAAGCTTGATGGCTTTATGGGTAGAATTCGATCTGTCTATCCAGTTGCGTCACCAAATGAATGCAACCAAATGTGCCTTTCAACTCTCATGAAGTGTGATCATTGTGGTGAAACTTCATGGCAGACGGGCGATTTTGTTAAAGCCACTTGCGAATTTTGTGGCACTGAGAATTTGACTAAAGAAGGTGCCACTACTTGTGGTTACTTACCCCAAAATGCTGTTGTTAAAATTTATTGTCCAGCATGTCACAATTCAGAAGTAGGACCTGAGCATAGTCTTGCCGAATACCATAATGAATCTGGCTTGAAAACCATTCTTCGTAAGGGTGGTCGCACTATTGCCTTTGGAGGCTGTGTGTTCTCTTATGTTGGTTGCCATAACAAGTGTGCCTATTGGGTTCCACGTGCTAGCGCTAACATAGGTTGTAACCATACAGGTGTTGTTGGAGAAGGTTCCGAAGGTCTTAATGACAACCTTCTTGAAATACTCCAAAAAGAGAAAGTCAACATCAATATTGTTGGTGACTTTAAACTTAATGAAGAGATCGCCATTATTTTGGCATCTTTTTCTGCTTCCACAAGTGCTTTTGTGGAAACTGTGAAAGGTTTGGATTATAAAGCATTCAAACAAATTGTTGAATCCTGTGGTAATTTTAAAGTTACAAAAGGAAAAGCTAAAAAAGGTGCCTGGAATATTGGTGAACAGAAATCAATACTGAGTCCTCTTTATGCATTTGCATCAGAGGCTGCTCGTGTTGTACGATCAATTTTCTCCCGCACTCTTGAAACTGCTCAAAATTCTGTGCGTGTTTTACAGAAGGCCGCTATAACAATACTAGATGGAATTTCACAGTATTCACTGAGACTCATTGATGCTATGATGTTCACATCTGATTTGGCTACTAACAATCTAGTTGTAATGGCCTACATTACAGGTGGTGTTGTTCAGTTGACTTCGCAGTGGCTAACTAACATCTTTGGCACTGTTTATGAAAAACTCAAACCCGTCCTTGATTGGCTTGAAGAGAAGTTTAAGGAAGGTGTAGAGTTTCTTAGAGACGGTTGGGAAATTGTTAAATTTATCTCAACCTGTGCTTGTGAAATTGTCGGTGGACAAATTGTCACCTGTGCAAAGGAAATTAAGGAGAGTGTTCAGACATTCTTTAAGCTTGTAAATAAATTTTTGGCTTTGTGTGCTGACTCTATCATTATTGGTGGAGCTAAACTTAAAGCCTTGAATTTAGGTGAAACATTTGTCACGCACTCAAAGGGATTGTACAGAAAGTGTGTTAAATCCAGAGAAGAAACTGGCCTACTCATGCCTCTAAAAGCCCCAAAAGAAATTATCTTCTTAGAGGGAGAAACACTTCCCACAGAAGTGTTAACAGAGGAAGTTGTCTTGAAAACTGGTGATTTACAACCATTAGAACAACCTACTAGTGAAGCTGTTGAAGCTCCATTGGTTGGTACACCAGTTTGTATTAACGGGCTTATGTTGCTCGAAATCAAAGACACAGAAAAGTACTGTGCCCTTGCACCTAATATGATGGTAACAAACAATACCTTCACACTCAAAGGCGGTGCACCAACAAAGGTTACTTTTGGTGATGACACTGTGATAGAAGTGCAAGGTTACAAGAGTGTGAATATCACTTTTGAACTTGATGAAAGGATTGATAAAGTACTTAATGAGAAGTGCTCTGCCTATACAGTTGAACTCGGTACAGAAGTAAATGAGTTCGCCTGTGTTGTGGCAGATGCTGTCATAAAAACTTTGCAACCAGTATCTGAATTACTTACACCACTGGGCATTGATTTAGATGAGTGGAGTATGGCTACATACTACTTATTTGATGAGTCTGGTGAGTTTAAATTGGCTTCACATATGTATTGTTCTTTCTACCCTCCAGATGAGGATGAAGAAGAAGGTGATTGTGAAGAAGAAGAGTTTGAGCCATCAACTCAATATGAGTATGGTACTGAAGATGATTACCAAGGTAAACCTTTGGAATTTGGTGCCACTTCTGCTGCTCTTCAACCTGAAGAAGAGCAAGAAGAAGATTGGTTAGATGATGATAGTCAACAAACTGTTGGTCAACAAGACGGCAGTGAGGACAATCAGACAACTACTATTCAAACAATTGTTGAGGTTCAACCTCAATTAGAGATGGAACTTACACCAGTTGTTCAGACTATTGAAGTGAATAGTTTTAGTGGTTATTTAAAACTTACTGACAATGTATACATTAAAAATGCAGACATTGTGGAAGAAGCTAAAAAGGTAAAACCAACAGTGGTTGTTAATGCAGCCAATGTTTACCTTAAACATGGAGGAGGTGTTGCAGGAGCCTTAAATAAGGCTACTAACAATGCCATGCAAGTTGAATCTGATGATTACATAGCTACTAATGGACCACTTAAAGTGGGTGGTAGTTGTGTTTTAAGCGGACACAATCTTGCTAAACACTGTCTTCATGTTGTCGGCCCAAATGTTAACAAAGGTGAAGACATTCAACTTCTTAAGAGTGCTTATGAAAATTTTAATCAGCACGAAGTTCTACTTGCACCATTATTATCAGCTGGTATTTTTGGTGCTGACCCTATACATTCTTTAAGAGTTTGTGTAGATACTGTTCGCACAAATGTCTACTTAGCTGTCTTTGATAAAAATCTCTATGACAAACTTGTTTCAAGCTTTTTGGAAATGAAGAGTGAAAAGCAAGTTGAACAAAAGATCGCTGAGATTCCTAAAGAGGAAGTTAAGCCATTTATAACTGAAAGTAAACCTTCAGTTGAACAGAGAAAACAAGATGATAAGAAAATCAAAGCTTGTGTTGAAGAAGTTACAACAACTCTGGAAGAAACTAAGTTCCTCACAGAAAACTTGTTACTTTATATTGACATTAATGGCAATCTTCATCCAGATTCTGCCACTCTTGTTAGTGACATTGACATCACTTTCTTAAAGAAAGATGCTCCATATATAGTGGGTGATGTTGTTCAAGAGGGTGTTTTAACTGCTGTGGTTATACCTACTAAAAAGGCTGGTGGCACTACTGAAATGCTAGCGAAAGCTTTGAGAAAAGTGCCAACAGACAATTATATAACCACTTACCCGGGTCAGGGTTTAAATGGTTACACTGTAGAGGAGGCAAAGACAGTGCTTAAAAAGTGTAAAAGTGCCTTTTACATTCTACCATCTATTATCTCTAATGAGAAGCAAGAAATTCTTGGAACTGTTTCTTGGAATTTGCGAGAAATGCTTGCACATGCAGAAGAAACACGCAAATTAATGCCTGTCTGTGTGGAAACTAAAGCCATAGTTTCAACTATACAGCGTAAATATAAGGGTATTAAAATACAAGAGGGTGTGGTTGATTATGGTGCTAGATTTTACTTTTACACCAGTAAAACAACTGTAGCGTCACTTATCAACACACTTAACGATCTAAATGAAACTCTTGTTACAATGCCACTTGGCTATGTAACACATGGCTTAAATTTGGAAGAAGCTGCTCGGTATATGAGATCTCTCAAAGTGCCAGCTACAGTTTCTGTTTCTTCACCTGATGCTGTTACAGCGTATAATGGTTATCTTACTTCTTCTTCTAAAACACCTGAAGAACATTTTATTGAAACCATCTCACTTGCTGGTTCCTATAAAGATTGGTCCTATTCTGGACAATCTACACAACTAGGTATAGAATTTCTTAAGAGAGGTGATAAAAGTGTATATTACACTAGTAATCCTACCACATTCCACCTAGATGGTGAAGTTATCACCTTTGACAATCTTAAGACACTTCTTTCTTTGAGAGAAGTGAGGACTATTAAGGTGTTTACAACAGTAGACAACATTAACCTCCACACGCAAGTTGTGGACATGTCAATGACATATGGACAACAGTTTGGTCCAACTTATTTGGATGGAGCTGATGTTACTAAAATAAAACCTCATAATTCACATGAAGGTAAAACATTTTATGTTTTACCTAATGATGACACTCTACGTGTTGAGGCTTTTGAGTACTACCACACAACTGATCCTAGTTTTCTGGGTAGGTACATGTCAGCATTAAATCACACTAAAAAGTGGAAATACCCACAAGTTAATGGTTTAACTTCTATTAAATGGGCAGATAACAACTGTTATCTTGCCACTGCATTGTTAACACTCCAACAAATAGAGTTGAAGTTTAATCCACCTGCTCTACAAGATGCTTATTACAGAGCAAGGGCTGGTGAAGCTGCTAACTTTTGTGCACTTATCTTAGCCTACTGTAATAAGACAGTAGGTGAGTTAGGTGATGTTAGAGAAACAATGAGTTACTTGTTTCAACATGCCAATTTAGATTCTTGCAAAAGAGTCTTGAACGTGGTGTGTAAAACTTGTGGACAACAGCAGACAACCCTTAAGGGTGTAGAAGCTGTTATGTACATGGGCACACTTTCTTATGAACAATTTAAGAAAGGTGTTCAGATACCTTGTACGTGTGGTAAACAAGCTACAAAATATCTAGTACAACAGGAGTCACCTTTTGTTATGATGTCAGCACCACCTGCTCAGTATGAACTTAAGCATGGTACATTTACTTGTGCTAGTGAGTACACTGGTAATTACCAGTGTGGTCACTATAAACATATAACTTCTAAAGAAACTTTGTATTGCATAGACGGTGCTTTACTTACAAAGTCCTCAGAATACAAAGGTCCTATTACGGATGTTTTCTACAAAGAAAACAGTTACACAACAACCATAAAACCAGTTACTTATAAATTGGATGGTGTTGTTTGTACAGAAATTGACCCTAAGTTGGACAATTATTATAAGAAAGACAATTCTTATTTCACAGAGCAACCAATTGATCTTGTACCAAACCAACCATATCCAAACGCAAGCTTCGATAATTTTAAGTTTGTATGTGATAATATCAAATTTGCTGATGATTTAAACCAGTTAACTGGTTATAAGAAACCTGCTTCAAGAGAGCTTAAAGTTACATTTTTCCCTGACTTAAATGGTGATGTGGTGGCTATTGATTATAAACACTACACACCCTCTTTTAAGAAAGGAGCTAAATTGTTACATAAACCTATTGTTTGGCATGTTAACAATGCAACTAATAAAGCCACGTATAAACCAAATACCTGGTGTATACGTTGTCTTTGGAGCACAAAACCAGTTGAAACATCAAATTCGTTTGATGTACTGAAGTCAGAGGACGCGCAGGGAATGGATAATCTTGCCTGCGAAGATCTAAAACCAGTCTCTGAAGAAGTAGTGGAAAATCCTACCATACAGAAAGACGTTCTTGAGTGTAATGTGAAAACTACCGAAGTTGTAGGAGACATTATACTTAAACCAGCAAATAATAGTTTAAAAATTACAGAAGAGGTTGGCCACACAGATCTAATGGCTGCTTATGTAGACAATTCTAGTCTTACTATTAAGAAACCTAATGAATTATCTAGAGTATTAGGTTTGAAAACCCTTGCTACTCATGGTTTAGCTGCTGTTAATAGTGTCCCTTGGGATACTATAGCTAATTATGCTAAGCCTTTTCTTAACAAAGTTGTTAGTACAACTACTAACATAGTTACACGGTGTTTAAACCGTGTTTGTACTAATTATATGCCTTATTTCTTTACTTTATTGCTACAATTGTGTACTTTTACTAGAAGTACAAATTCTAGAATTAAAGCATCTATGCCGACTACTATAGCAAAGAATACTGTTAAGAGTGTCGGTAAATTTTGTCTAGAGGCTTCATTTAATTATTTGAAGTCACCTAATTTTTCTAAACTGATAAATATTATAATTTGGTTTTTACTATTAAGTGTTTGCCTAGGTTCTTTAATCTACTCAACCGCTGCTTTAGGTGTTTTAATGTCTAATTTAGGCATGCCTTCTTACTGTACTGGTTACAGAGAAGGCTATTTGAACTCTACTAATGTCACTATTGCAACCTACTGTACTGGTTCTATACCTTGTAGTGTTTGTCTTAGTGGTTTAGATTCTTTAGACACCTATCCTTCTTTAGAAACTATACAAATTACCATTTCATCTTTTAAATGGGATTTAACTGCTTTTGGCTTAGTTGCAGAGTGGTTTTTGGCATATATTCTTTTCACTAGGTTTTTCTATGTACTTGGATTGGCTGCAATCATGCAATTGTTTTTCAGCTATTTTGCAGTACATTTTATTAGTAATTCTTGGCTTATGTGGTTAATAATTAATCTTGTACAAATGGCCCCGATTTCAGCTATGGTTAGAATGTACATCTTCTTTGCATCATTTTATTATGTATGGAAAAGTTATGTGCATGTTGTAGACGGTTGTAATTCATCAACTTGTATGATGTGTTACAAACGTAATAGAGCAACAAGAGTCGAATGTACAACTATTGTTAATGGTGTTAGAAGGTCCTTTTATGTCTATGCTAATGGAGGTAAAGGCTTTTGCAAACTACACAATTGGAATTGTGTTAATTGTGATACATTCTGTGCTGGTAGTACATTTATTAGTGATGAAGTTGCGAGAGACTTGTCACTACAGTTTAAAAGACCAATAAATCCTACTGACCAGTCTTCTTACATCGTTGATAGTGTTACAGTGAAGAATGGTTCCATCCATCTTTACTTTGATAAAGCTGGTCAAAAGACTTATGAAAGACATTCTCTCTCTCATTTTGTTAACTTAGACAACCTGAGAGCTAATAACACTAAAGGTTCATTGCCTATTAATGTTATAGTTTTTGATGGTAAATCAAAATGTGAAGAATCATCTGCAAAATCAGCGTCTGTTTACTACAGTCAGCTTATGTGTCAACCTATACTGTTACTAGATCAGGCATTAGTGTCTGATGTTGGTGATAGTGCGGAAGTTGCAGTTAAAATGTTTGATGCTTACGTTAATACGTTTTCATCAACTTTTAACGTACCAATGGAAAAACTCAAAACACTAGTTGCAACTGCAGAAGCTGAACTTGCAAAGAATGTGTCCTTAGACAATGTCTTATCTACTTTTATTTCAGCAGCTCGGCAAGGGTTTGTTGATTCAGATGTAGAAACTAAAGATGTTGTTGAATGTCTTAAATTGTCACATCAATCTGACATAGAAGTTACTGGCGATAGTTGTAATAACTATATGCTCACCTATAACAAAGTTGAAAACATGACACCCCGTGACCTTGGTGCTTGTATTGACTGTAGTGCGCGTCATATTAATGCGCAGGTAGCAAAAAGTCACAACATTGCTTTGATATGGAACGTTAAAGATTTCATGTCATTGTCTGAACAACTACGAAAACAAATACGTAGTGCTGCTAAAAAGAATAACTTACCTTTTAAGTTGACATGTGCAACTACTAGACAAGTTGTTAATGTTGTAACAACAAAGATAGCACTTAAGGGTGGTAAAATTGTTAATAATTGGTTGAAGCAGTTAATTAAAGTTACACTTGTGTTCCTTTTTGTTGCTGCTATTTTCTATTTAATAACACCTGTTCATGTCATGTCTAAACATACTGACTTTTCAAGTGAAATCATAGGATACAAGGCTATTGATGGTGGTGTCACTCGTGACATAGCATCTACAGATACTTGTTTTGCTAACAAACATGCTGATTTTGACACATGGTTTAGCCAGCGTGGTGGTAGTTATACTAATGACAAAGCTTGCCCATTGATTGCTGCAGTCATAACAAGAGAAGTGGGTTTTGTCGTGCCTGGTTTGCCTGGCACGATATTACGCACAACTAATGGTGACTTTTTGCATTTCTTACCTAGAGTTTTTAGTGCAGTTGGTAACATCTGTTACACACCATCAAAACTTATAGAGTACACTGACTTTGCAACATCAGCTTGTGTTTTGGCTGCTGAATGTACAATTTTTAAAGATGCTTCTGGTAAGCCAGTACCATATTGTTATGATACCAATGTACTAGAAGGTTCTGTTGCTTATGAAAGTTTACGCCCTGACACACGTTATGTGCTCATGGATGGCTCTATTATTCAATTTCCTAACACCTACCTTGAAGGTTCTGTTAGAGTGGTAACAACTTTTGATTCTGAGTACTGTAGGCACGGCACTTGTGAAAGATCAGAAGCTGGTGTTTGTGTATCTACTAGTGGTAGATGGGTACTTAACAATGATTATTACAGATCTTTACCAGGAGTTTTCTGTGGTGTAGATGCTGTAAATTTACTTACTAATATGTTTACACCACTAATTCAACCTATTGGTGCTTTGGACATATCAGCATCTATAGTAGCTGGTGGTATTGTAGCTATCGTAGTAACATGCCTTGCCTACTATTTTATGAGGTTTAGAAGAGCTTTTGGTGAATACAGTCATGTAGTTGCCTTTAATACTTTACTATTCCTTATGTCATTCACTGTACTCTGTTTAACACCAGTTTACTCATTCTTACCTGGTGTTTATTCTGTTATTTACTTGTACTTGACATTTTATCTTACTAATGATGTTTCTTTTTTAGCACATATTCAGTGGATGGTTATGTTCACACCTTTAGTACCTTTCTGGATAACAATTGCTTATATCATTTGTATTTCCACAAAGCATTTCTATTGGTTCTTTAGTAATTACCTAAAGAGACGTGTAGTCTTTAATGGTGTTTCCTTTAGTACTTTTGAAGAAGCTGCGCTGTGCACCTTTTTGTTAAATAAAGAAATGTATCTAAAGTTGCGTAGTGATGTGCTATTACCTCTTACGCAATATAATAGATACTTAGCTCTTTATAATAAGTACAAGTATTTTAGTGGAGCAATGGATACAACTAGCTACAGAGAAGCTGCTTGTTGTCATCTCGCAAAGGCTCTCAATGACTTCAGTAACTCAGGTTCTGATGTTCTTTACCAACCACCACAAACCTCTATCACCTCAGCTGTTTTGCAGAGTGGTTTTAGAAAAATGGCATTCCCATCTGGTAAAGTTGAGGGTTGTATGGTACAAGTAACTTGTGGTACAACTACACTTAACGGTCTTTGGCTTGATGACGTAGTTTACTGTCCAAGACATGTGATCTGCACCTCTGAAGACATGCTTAACCCTAATTATGAAGATTTACTCATTCGTAAGTCTAATCATAATTTCTTGGTACAGGCTGGTAATGTTCAACTCAGGGTTATTGGACATTCTATGCAAAATTGTGTACTTAAGCTTAAGGTTGATACAGCCAATCCTAAGACACCTAAGTATAAGTTTGTTCGCATTCAACCAGGACAGACTTTTTCAGTGTTAGCTTGTTACAATGGTTCACCATCTGGTGTTTACCAATGTGCTATGAGGCCCAATTTCACTATTAAGGGTTCATTCCTTAATGGTTCATGTGGTAGTGTTGGTTTTAACATAGATTATGACTGTGTCTCTTTTTGTTACATGCACCATATGGAATTACCAACTGGAGTTCATGCTGGCACAGACTTAGAAGGTAACTTTTATGGACCTTTTGTTGACAGGCAAACAGCACAAGCAGCTGGTACGGACACAACTATTACAGTTAATGTTTTAGCTTGGTTGTACGCTGCTGTTATAAATGGAGACAGGTGGTTTCTCAATCGATTTACCACAACTCTTAATGACTTTAACCTTGTGGCTATGAAGTACAATTATGAACCTCTAACACAAGACCATGTTGACATACTAGGACCTCTTTCTGCTCAAACTGGAATTGCCGTTTTAGATATGTGTGCTTCATTAAAAGAATTACTGCAAAATGGTATGAATGGACGTACCATATTGGGTAGTGCTTTATTAGAAGATGAATTTACACCTTTTGATGTTGTTAGACAATGCTCAGGTGTTACTTTCCAAAGTGCAGTGAAAAGAACAATCAAGGGTACACACCACTGGTTGTTACTCACAATTTTGACTTCACTTTTAGTTTTAGTCCAGAGTACTCAATGGTCTTTGTTCTTTTTTTTGTATGAAAATGCCTTTTTACCTTTTGCTATGGGTATTATTGCTATGTCTGCTTTTGCAATGATGTTTGTCAAACATAAGCATGCATTTCTCTGTTTGTTTTTGTTACCTTCTCTTGCCACTGTAGCTTATTTTAATATGGTCTATATGCCTGCTAGTTGGGTGATGCGTATTATGACATGGTTGGATATGGTTGATACTAGTTTGTCTGGTTTTAAGCTAAAAGACTGTGTTATGTATGCATCAGCTGTAGTGTTACTAATCCTTATGACAGCAAGAACTGTGTATGATGATGGTGCTAGGAGAGTGTGGACACTTATGAATGTCTTGACACTCGTTTATAAAGTTTATTATGGTAATGCTTTAGATCAAGCCATTTCCATGTGGGCTCTTATAATCTCTGTTACTTCTAACTACTCAGGTGTAGTTACAACTGTCATGTTTTTGGCCAGAGGTATTGTTTTTATGTGTGTTGAGTATTGCCCTATTTTCTTCATAACTGGTAATACACTTCAGTGTATAATGCTAGTTTATTGTTTCTTAGGCTATTTTTGTACTTGTTACTTTGGCCTCTTTTGTTTACTCAACCGCTACTTTAGACTGACTCTTGGTGTTTATGATTACTTAGTTTCTACACAGGAGTTTAGATATATGAATTCACAGGGACTACTCCCACCCAAGAATAGCATAGATGCCTTCAAACTCAACATTAAATTGTTGGGTGTTGGTGGCAAACCTTGTATCAAAGTAGCCACTGTACAGTCTAAAATGTCAGATGTAAAGTGCACATCAGTAGTCTTACTCTCAGTTTTGCAACAACTCAGAGTAGAATCATCATCTAAATTGTGGGCTCAATGTGTCCAGTTACACAATGACATTCTCTTAGCTAAAGATACTACTGAAGCCTTTGAAAAAATGGTTTCACTACTTTCTGTTTTGCTTTCCATGCAGGGTGCTGTAGACATAAACAAGCTTTGTGAAGAAATGCTGGACAACAGGGCAACCTTACAAGCTATAGCCTCAGAGTTTAGTTCCCTTCCATCATATGCAGCTTTTGCTACTGCTCAAGAAGCTTATGAGCAGGCTGTTGCTAATGGTGATTCTGAAGTTGTTCTTAAAAAGTTGAAGAAGTCTTTGAATGTGGCTAAATCTGAATTTGACCGTGATGCAGCCATGCAACGTAAGTTGGAAAAGATGGCTGATCAAGCTATGACCCAAATGTATAAACAGGCTAGATCTGAGGACAAGAGGGCAAAAGTTACTAGTGCTATGCAGACAATGCTTTTCACTATGCTTAGAAAGTTGGATAATGATGCACTCAACAACATTATCAACAATGCAAGAGATGGTTGTGTTCCCTTGAACATAATACCTCTTACAACAGCAGCCAAACTAATGGTTGTCATACCAGACTATAACACATATAAAAATACGTGTGATGGTACAACATTTACTTATGCATCAGCATTGTGGGAAATCCAACAGGTTGTAGATGCAGATAGTAAAATTGTTCAACTTAGTGAAATTAGTATGGACAATTCACCTAATTTAGCATGGCCTCTTATTGTAACAGCTTTAAGGGCCAATTCTGCTGTCAAATTACAGAATAATGAGCTTAGTCCTGTTGCACTACGACAGATGTCTTGTGCTGCCGGTACTACACAAACTGCTTGCACTGATGACAATGCGTTAGCTTACTACAACACAACAAAGGGAGGTAGGTTTGTACTTGCACTGTTATCCGATTTACAGGATTTGAAATGGGCTAGATTCCCTAAGAGTGATGGAACTGGTACTATCTATACAGAACTGGAACCACCTTGTAGGTTTGTTACAGACACACCTAAAGGTCCTAAAGTGAAGTATTTATACTTTATTAAAGGATTAAACAACCTAAATAGAGGTATGGTACTTGGTAGTTTAGCTGCCACAGTACGTCTACAAGCTGGTAATGCAACAGAAGTGCCTGCCAATTCAACTGTATTATCTTTCTGTGCTTTTGCTGTAGATGCTGCTAAAGCTTACAAAGATTATCTAGCTAGTGGGGGACAACCAATCACTAATTGTGTTAAGATGTTGTGTACACACACTGGTACTGGTCAGGCAATAACAGTTACACCGGAAGCCAATATGGATCAAGAATCCTTTGGTGGTGCATCGTGTTGTCTGTACTGCCGTTGCCACATAGATCATCCAAATCCTAAAGGATTTTGTGACTTAAAAGGTAAGTATGTACAAATACCTACAACTTGTGCTAATGACCCTGTGGGTTTTACACTTAAAAACACAGTCTGTACCGTCTGCGGTATGTGGAAAGGTTATGGCTGTAGTTGTGATCAACTCCGCGAACCCATGCTTCAGTCAGCTGATGCACAATCGTTTTTAAACGGGTTTGCGGTGTAAGTGCAGCCCGTCTTACACCGTGCGGCACAGGCACTAGTACTGATGTCGTATACAGGGCTTTTGACATCTACAATGATAAAGTAGCTGGTTTTGCTAAATTCCTAAAAACTAATTGTTGTCGCTTCCAAGAAAAGGACGAAGATGACAATTTAATTGATTCTTACTTTGTAGTTAAGAGACACACTTTCTCTAACTACCAACATGAAGAAACAATTTATAATTTACTTAAGGATTGTCCAGCTGTTGCTAAACATGACTTCTTTAAGTTTAGAATAGACGGTGACATGGTACCACATATATCACGTCAACGTCTTACTAAATACACAATGGCAGACCTCGTCTATGCTTTAAGGCATTTTGATGAAGGTAATTGTGACACATTAAAAGAAATACTTGTCACATACAATTGTTGTGATGATGATTATTTCAATAAAAAGGACTGGTATGATTTTGTAGAAAACCCAGATATATTACGCGTATACGCCAACTTAGGTGAACGTGTACGCCAAGCTTTGTTAAAAACAGTACAATTCTGTGATGCCATGCGAAATGCTGGTATTGTTGGTGTACTGACATTAGATAATCAAGATCTCAATGGTAACTGGTATGATTTCGGTGATTTCATACAAACCACGCCAGGTAGTGGAGTTCCTGTTGTAGATTCTTATTATTCATTGTTAATGCCTATATTAACCTTGACCAGGGCTTTAACTGCAGAGTCACATGTTGACACTGACTTAACAAAGCCTTACATTAAGTGGGATTTGTTAAAATATGACTTCACGGAAGAGAGGTTAAAACTCTTTGACCGTTATTTTAAATATTGGGATCAGACATACCACCCAAATTGTGTTAACTGTTTGGATGACAGATGCATTCTGCATTGTGCAAACTTTAATGTTTTATTCTCTACAGTGTTCCCACCTACAAGTTTTGGACCACTAGTGAGAAAAATATTTGTTGATGGTGTTCCATTTGTAGTTTCAACTGGATACCACTTCAGAGAGCTAGGTGTTGTACATAATCAGGATGTAAACTTACATAGCTCTAGACTTAGTTTTAAGGAATTACTTGTGTATGCTGCTGACCCTGCTATGCACGCTGCTTCTGGTAATCTATTACTAGATAAACGCACTACGTGCTTTTCAGTAGCTGCACTTACTAACAATGTTGCTTTTCAAACTGTCAAACCCGGTAATTTTAACAAAGACTTCTATGACTTTGCTGTGTCTAAGGGTTTCTTTAAGGAAGGAAGTTCTGTTGAATTAAAACACTTCTTCTTTGCTCAGGATGGTAATGCTGCTATCAGCGATTATGACTACTATCGTTATAATCTACCAACAATGTGTGATATCAGACAACTACTATTTGTAGTTGAAGTTGTTGATAAGTACTTTGATTGTTACGATGGTGGCTGTATTAATGCTAACCAAGTCATCGTCAACAACCTAGACAAATCAGCTGGTTTTCCATTTAATAAATGGGGTAAGGCTAGACTTTATTATGATTCAATGAGTTATGAGGATCAAGATGCACTTTTCGCATATACAAAACGTAATGTCATCCCTACTATAACTCAAATGAATCTTAAGTATGCCATTAGTGCAAAGAATAGAGCTCGCACCGTAGCTGGTGTCTCTATCTGTAGTACTATGACCAATAGACAGTTTCATCAAAAATTATTGAAATCAATAGCCGCCACTAGAGGAGCTACTGTAGTAATTGGAACAAGCAAATTCTATGGTGGTTGGCACAACATGTTAAAAACTGTTTATAGTGATGTAGAAAACCCTCACCTTATGGGTTGGGATTATCCTAAATGTGATAGAGCCATGCCTAACATGCTTAGAATTATGGCCTCACTTGTTCTTGCTCGCAAACATACAACGTGTTGTAGCTTGTCACACCGTTTCTATAGATTAGCTAATGAGTGTGCTCAAGTATTGAGTGAAATGGTCATGTGTGGCGGTTCACTATATGTTAAACCAGGTGGAACCTCATCAGGAGATGCCACAACTGCTTATGCTAATAGTGTTTTTAACATTTGTCAAGCTGTCACGGCCAATGTTAATGCACTTTTATCTACTGATGGTAACAAAATTGCCGATAAGTATGTCCGCAATTTACAACACAGACTTTATGAGTGTCTCTATAGAAATAGAGATGTTGACACAGACTTTGTGAATGAGTTTTACGCATATTTGCGTAAACATTTCTCAATGATGATACTCTCTGACGATGCTGTTGTGTGTTTCAATAGCACTTATGCATCTCAAGGTCTAGTGGCTAGCATAAAGAACTTTAAGTCAGTTCTTTATTATCAAAACAATGTTTTTATGTCTGAAGCAAAATGTTGGACTGAGACTGACCTTACTAAAGGACCTCATGAATTTTGCTCTCAACATACAATGCTAGTTAAACAGGGTGATGATTATGTGTACCTTCCTTACCCAGATCCATCAAGAATCCTAGGGGCCGGCTGTTTTGTAGATGATATCGTAAAAACAGATGGTACACTTATGATTGAACGGTTCGTGTCTTTAGCTATAGATGCTTACCCACTTACTAAACATCCTAATCAGGAGTATGCTGATGTCTTTCATTTGTACTTACAATACATAAGAAAGCTACATGATGAGTTAACAGGACACATGTTAGACATGTATTCTGTTATGCTTACTAATGATAACACTTCAAGGTATTGGGAACCTGAGTTTTATGAGGCTATGTACACACCGCATACAGTCTTACAGGCTGTTGGGGCTTGTGTTCTTTGCAATTCACAGACTTCATTAAGATGTGGTGCTTGCATACGTAGACCATTCTTATGTTGTAAATGCTGTTACGACCATGTCATATCAACATCACATAAATTAGTCTTGTCTGTTAATCCGTATGTTTGCAATGCTCCAGGTTGTGATGTCACAGATGTGACTCAACTTTACTTAGGAGGTATGAGCTATTATTGTAAATCACATAAACCACCCATTAGTTTTCCATTGTGTGCTAATGGACAAGTTTTTGGTTTATATAAAAATACATGTGTTGGTAGCGATAATGTTACTGACTTTAATGCAATTGCAACATGTGACTGGACAAATGCTGGTGATTACATTTTAGCTAACACCTGTACTGAAAGACTCAAGCTTTTTGCAGCAGAAACGCTCAAAGCTACTGAGGAGACATTTAAACTGTCTTATGGTATTGCTACTGTACGTGAAGTGCTGTCTGACAGAGAATTACATCTTTCATGGGAAGTTGGTAAACCTAGACCACCACTTAACCGAAATTATGTCTTTACTGGTTATCGTGTAACTAAAAACAGTAAAGTACAAATAGGAGAGTACACCTTTGAAAAAGGTGACTATGGTGATGCTGTTGTTTACCGAGGTACAACAACTTACAAATTAAATGTTGGTGATTATTTTGTGCTGACATCACATACAGTAATGCCATTAAGTGCACCTACACTAGTGCCACAAGAGCACTATGTTAGAATTACTGGCTTATACCCAACACTCAATATCTCAGATGAGTTTTCTAGCAATGTTGCAAATTATCAAAAGGTTGGTATGCAAAAGTATTCTACACTCCAGGGACCACCTGGTACTGGTAAGAGTCATTTTGCTATTGGCCTAGCTCTCTACTACCCTTCTGCTCGCATAGTGTATACAGCTTGCTCTCATGCCGCTGTTGATGCACTATGTGAGAAGGCATTAAAATATTTGCCTATAGATAAATGTAGTAGAATTATACCTGCACGTGCTCGTGTAGAGTGTTTTGATAAATTCAAAGTGAATTCAACATTAGAACAGTATGTCTTTTGTACTGTAAATGCATTGCCTGAGACGACAGCAGATATAGTTGTCTTTGATGAAATTTCAATGGCCACAAATTATGATTTGAGTGTTGTCAATGCCAGATTACGTGCTAAGCACTATGTGTACATTGGCGACCCTGCTCAATTACCTGCACCACGCACATTGCTAACTAAGGGCACACTAGAACCAGAATATTTCAATTCAGTGTGTAGACTTATGAAAACTATAGGTCCAGACATGTTCCTCGGAACTTGTCGGCGTTGTCCTGCTGAAATTGTTGACACTGTGAGTGCTTTGGTTTATGATAATAAGCTTAAAGCACATAAAGACAAATCAGCTCAATGCTTTAAAATGTTTTATAAGGGTGTTATCACGCATGATGTTTCATCTGCAATTAACAGGCCACAAATAGGCGTGGTAAGAGAATTCCTTACACGTAACCCTGCTTGGAGAAAAGCTGTCTTTATTTCACCTTATAATTCACAGAATGCTGTAGCCTCAAAGATTTTGGGACTACCAACTCAAACTGTTGATTCATCACAGGGCTCAGAATATGACTATGTCATATTCACTCAAACCACTGAAACAGCTCACTCTTGTAATGTAAACAGATTTAATGTTGCTATTACCAGAGCAAAAGTAGGCATACTTTGCATAATGTCTGATAGAGACCTTTATGACAAGTTGCAATTTACAAGTCTTGAAATTCCACGTAGGAATGTGGCAACTTTACAAGCTGAAAATGTAACAGGACTCTTTAAAGATTGTAGTAAGGTAATCACTGGGTTACATCCTACACAGGCACCTACACACCTCAGTGTTGACACTAAATTCAAAACTGAAGGTTTATGTGTTGACATACCTGGCATACCTAAGGACATGACCTATAGAAGACTCATCTCTATGATGGGTTTTAAAATGAATTATCAAGTTAATGGTTACCCTAACATGTTTATCACCCGCGAAGAAGCTATAAGACATGTACGTGCATGGATTGGCTTCGATGTCGAGGGGTGTCATGCTACTAGAGAAGCTGTTGGTACCAATTTACCTTTACAGCTAGGTTTTTCTACAGGTGTTAACCTAGTTGCTGTACCTACAGGTTATGTTGATACACCTAATAATACAGATTTTTCCAGAGTTAGTGCTAAACCACCGCCTGGAGATCAATTTAAACACCTCATACCACTTATGTACAAAGGACTTCCTTGGAATGTAGTGCGTATAAAGATTGTACAAATGTTAAGTGACACACTTAAAAATCTCTCTGACAGAGTCGTATTTGTCTTATGGGCACATGGCTTTGAGTTGACATCTATGAAGTATTTTGTGAAAATAGGACCTGAGCGCACCTGTTGTCTATGTGATAGACGTGCCACATGCTTTTCCACTGCTTCAGACACTTATGCCTGTTGGCATCATTCTATTGGATTTGATTACGTCTATAATCCGTTTATGATTGATGTTCAACAATGGGGTTTTACAGGTAACCTACAAAGCAACCATGATCTGTATTGTCAAGTCCATGGTAATGCACATGTAGCTAGTTGTGATGCAATCATGACTAGGTGTCTAGCTGTCCACGAGTGCTTTGTTAAGCGTGTTGACTGGACTATTGAATATCCTATAATTGGTGATGAACTGAAGATTAATGCGGCTTGTAGAAAGGTTCAACACATGGTTGTTAAAGCTGCATTATTAGCAGACAAATTCCCAGTTCTTCACGACATTGGTAACCCTAAAGCTATTAAGTGTGTACCTCAAGCTGATGTAGAATGGAAGTTCTATGATGCACAGCCTTGTAGTGACAAAGCTTATAAAATAGAAGAATTATTCTATTCTTATGCCACACATTCTGACAAATTCACAGATGGTGTATGCCTATTTTGGAATTGCAATGTCGATAGATATCCTGCTAATTCCATTGTTTGTAGATTTGACACTAGAGTGCTATCTAACCTTAACTTGCCTGGTTGTGATGGTGGCAGTTTGTATGTAAATAAACATGCATTCCACACACCAGCTTTTGATAAAAGTGCTTTTGTTAATTTAAAACAATTACCATTTTTCTATTACTCTGACAGTCCATGTGAGTCTCATGGAAAACAAGTAGTGTCAGATATAGATTATGTACCACTAAAGTCTGCTACGTGTATAACACGTTGCAATTTAGGTGGTGCTGTCTGTAGACATCATGCTAATGAGTACAGATTGTATCTCGATGCTTATAACATGATGATCTCAGCTGGCTTTAGCTTGTGGGTTTACAAACAATTTGATACTTATAACCTCTGGAACACTTTTACAAGACTTCAGAGTTTAGAAAATGTGGCTTTTAATGTTGTAAATAAGGGACACTTTGATGGACAACAGGGTGAAGTACCAGTTTCTATCATTAATAACACTGTTTACACAAAAGTTGATGGTGTTGATGTAGAATTGTTTGAAAATAAAACAACATTACCTGTTAATGTAGCATTTGAGCTTTGGGCTAAGCGCAACATTAAACCAGTACCAGAGGTGAAAATACTCAATAATTTGGGTGTGGACATTGCTGCTAATACTGTGATCTGGGACTACAAAAGAGATGCTCCAGCACATATATCTACTATTGGTGTTTGTTCTATGACTGACATAGCCAAGAAACCAACTGAAACGATTTGTGCACCACTCACTGTCTTTTTTGATGGTAGAGTTGATGGTCAAGTAGACTTATTTAGAAATGCCCGTAATGGTGTTCTTATTACAGAAGGTAGTGTTAAAGGTTTACAACCATCTGTAGGTCCCAAACAAGCTAGTCTTAATGGAGTCACATTAATTGGAGAAGCCGTAAAAACACAGTTCAATTATTATAAGAAAGTTGATGGTGTTGTCCAACAATTACCTGAAACTTACTTTACTCAGAGTAGAAATTTACAAGAATTTAAACCCAGGAGTCAAATGGAAATTGATTTCTTAGAATTAGCTATGGATGAATTCATTGAACGGTATAAATTAGAAGGCTATGCCTTCGAACATATCGTTTATGGAGATTTTAGTCATAGTCAGTTAGGTGGTTTACATCTACTGATTGGACTAGCTAAACGTTTTAAGGAATCACCTTTTGAATTAGAAGATTTTATTCCTATGGACAGTACAGTTAAAAACTATTTCATAACAGATGCGCAAACAGGTTCATCTAAGTGTGTGTGTTCTGTTATTGATTTATTACTTGATGATTTTGTTGAAATAATAAAATCCCAAGATTTATCTGTAGTTTCTAAGGTTGTCAAAGTGACTATTGACTATACAGAAATTTCATTTATGCTTTGGTGTAAAGATGGCCATGTAGAAACATTTTACCCAAAATTACAATCTAGTCAAGCGTGGCAACCGGGTGTTGCTATGCCTAATCTTTACAAAATGCAAAGAATGCTATTAGAAAAGTGTGACCTTCAAAATTATGGTGATAGTGCAACATTACCTAAAGGCATAATGATGAATGTCGCAAAATATACTCAACTGTGTCAATATTTAAACACATTAACATTAGCTGTACCCTATAATATGAGAGTTATACATTTTGGTGCTGGTTCTGATAAAGGAGTTGCACCAGGTACAGCTGTTTTAAGACAGTGGTTGCCTACGGGTACGCTGCTTGTCGATTCAGATCTTAATGACTTTGTCTCTGATGCAGATTCAACTTTGATTGGTGATTGTGCAACTGTACATACAGCTAATAAATGGGATCTCATTATTAGTGATATGTACGACCCTAAGACTAAAAATGTTACAAAAGAAAATGACTCTAAAGAGGGTTTTTTCACTTACATTTGTGGGTTTATACAACAAAAGCTAGCTCTTGGAGGTTCCGTGGCTATAAAGATAACAGAACATTCTTGGAATGCTGATCTTTATAAGCTCATGGGACACTTCGCATGGTGGACAGCCTTTGTTACTAATGTGAATGCGTCATCATCTGAAGCATTTTTAATTGGATGTAATTATCTTGGCAAACCACGCGAACAAATAGATGGTTATGTCATGCATGCAAATTACATATTTTGGAGGAATACAAATCCAATTCAGTTGTCTTCCTATTCTTTATTTGACATGAGTAAATTTCCCCTTAAATTAAGGGGTACTGCTGTTATGTCTTTAAAAGAAGGTCAAATCAATGATATGATTTTATCTCTTCTTAGTAAAGGTAGACTTATAATTAGAGAAAACAACAGAGTTGTTATTTCTAGTGATGTTCTTGTTAACAACTAAACGAACAATGTTTGTTTTTCTTGTTTTATTGCCACTAGTCTCTAGTCAGTGTGTTAATCTTACAACCAGAACTCAATTACCCCCTGCATACACTAATTCTTTCACACGTGGTGTTTATTACCCTGACAAAGTTTTCAGATCCTCAGTTTTACATTCAACTCAGGACTTGTTCTTACCTTTCTTTTCCAATGTTACTTGGTTCCATGCTATACATGTCTCTGGGACCAATGGTACTAAGAGGTTTGATAACCCTGTCCTACCATTTAATGATGGTGTTTATTTTGCTTCCACTGAGAAGTCTAACATAATAAGAGGCTGGATTTTTGGTACTACTTTAGATTCGAAGACCCAGTCCCTACTTATTGTTAATAACGCTACTAATGTTGTTATTAAAGTCTGTGAATTTCAATTTTGTAATGATCCATTTTTGGGTGTTTATTACCACAAAAACAACAAAAGTTGGATGGAAAGTGAGTTCAGAGTTTATTCTAGTGCGAATAATTGCACTTTTGAATATGTCTCTCAGCCTTTTCTTATGGACCTTGAAGGAAAACAGGGTAATTTCAAAAATCTTAGGGAATTTGTGTTTAAGAATATTGATGGTTATTTTAAAATATATTCTAAGCACACGCCTATTAATTTAGTGCGTGATCTCCCTCAGGGTTTTTCGGCTTTAGAACCATTGGTAGATTTGCCAATAGGTATTAACATCACTAGGTTTCAAACTTTACTTGCTTTACATAGAAGTTATTTGACTCCTGGTGATTCTTCTTCAGGTTGGACAGCTGGTGCTGCAGCTTATTATGTGGGTTATCTTCAACCTAGGACTTTTCTATTAAAATATAATGAAAATGGAACCATTACAGATGCTGTAGACTGTGCACTTGACCCTCTCTCAGAAACAAAGTGTACGTTGAAATCCTTCACTGTAGAAAAAGGAATCTATCAAACTTCTAACTTTAGAGTCCAACCAACAGAATCTATTGTTAGATTTCCTAATATTACAAACTTGTGCCCTTTTGGTGAAGTTTTTAACGCCACCAGATTTGCATCTGTTTATGCTTGGAACAGGAAGAGAATCAGCAACTGTGTTGCTGATTATTCTGTCCTATATAATTCCGCATCATTTTCCACTTTTAAGTGTTATGGAGTGTCTCCTACTAAATTAAATGATCTCTGCTTTACTAATGTCTATGCAGATTCATTTGTAATTAGAGGTGATGAAGTCAGACAAATCGCTCCAGGGCAAACTGGAAAGATTGCTGATTATAATTATAAATTACCAGATGATTTTACAGGCTGCGTTATAGCTTGGAATTCTAACAATCTTGATTCTAAGGTTGGTGGTAATTATAATTACCTGTATAGATTGTTTAGGAAGTCTAATCTCAAACCTTTTGAGAGAGATATTTCAACTGAAATCTATCAGGCCGGTAGCACACCTTGTAATGGTGTTGAAGGTTTTAATTGTTACTTTCCTTTACAATCATATGGTTTCCAACCCACTAATGGTGTTGGTTACCAACCATACAGAGTAGTAGTACTTTCTTTTGAACTTCTACATGCACCAGCAACTGTTTGTGGACCTAAAAAGTCTACTAATTTGGTTAAAAACAAATGTGTCAATTTCAACTTCAATGGTTTAACAGGCACAGGTGTTCTTACTGAGTCTAACAAAAAGTTTCTGCCTTTCCAACAATTTGGCAGAGACATTGCTGACACTACTGATGCTGTCCGTGATCCACAGACACTTGAGATTCTTGACATTACACCATGTTCTTTTGGTGGTGTCAGTGTTATAACACCAGGAACAAATACTTCTAACCAGGTTGCTGTTCTTTATCAGGATGTTAACTGCACAGAAGTCCCTGTTGCTATTCATGCAGATCAACTTACTCCTACTTGGCGTGTTTATTCTACAGGTTCTAATGTTTTTCAAACACGTGCAGGCTGTTTAATAGGGGCTGAACATGTCAACAACTCATATGAGTGTGACATACCCATTGGTGCAGGTATATGCGCTAGTTATCAGACTCAGACTAATTCTCCTCGGCGGGCACGTAGTGTAGCTAGTCAATCCATCATTGCCTACACTATGTCACTTGGTGCAGAAAATTCAGTTGCTTACTCTAATAACTCTATTGCCATACCCACAAATTTTACTATTAGTGTTACCACAGAAATTCTACCAGTGTCTATGACCAAGACATCAGTAGATTGTACAATGTACATTTGTGGTGATTCAACTGAATGCAGCAATCTTTTGTTGCAATATGGCAGTTTTTGTACACAATTAAACCGTGCTTTAACTGGAATAGCTGTTGAACAAGACAAAAACACCCAAGAAGTTTTTGCACAAGTCAAACAAATTTACAAAACACCACCAATTAAAGATTTTGGTGGTTTTAATTTTTCACAAATATTACCAGATCCATCAAAACCAAGCAAGAGGTCATTTATTGAAGATCTACTTTTCAACAAAGTGACACTTGCAGATGCTGGCTTCATCAAACAATATGGTGATTGCCTTGGTGATATTGCTGCTAGAGACCTCATTTGTGCACAAAAGTTTAACGGCCTTACTGTTTTGCCACCTTTGCTCACAGATGAAATGATTGCTCAATACACTTCTGCACTGTTAGCGGGTACAATCACTTCTGGTTGGACCTTTGGTGCAGGTGCTGCATTACAAATACCATTTGCTATGCAAATGGCTTATAGGTTTAATGGTATTGGAGTTACACAGAATGTTCTCTATGAGAACCAAAAATTGATTGCCAACCAATTTAATAGTGCTATTGGCAAAATTCAAGACTCACTTTCTTCCACAGCAAGTGCACTTGGAAAACTTCAAGATGTGGTCAACCAAAATGCACAAGCTTTAAACACGCTTGTTAAACAACTTAGCTCCAATTTTGGTGCAATTTCAAGTGTTTTAAATGATATCCTTTCACGTCTTGACAAAGTTGAGGCTGAAGTGCAAATTGATAGGTTGATCACAGGCAGACTTCAAAGTTTGCAGACATATGTGACTCAACAATTAATTAGAGCTGCAGAAATCAGAGCTTCTGCTAATCTTGCTGCTACTAAAATGTCAGAGTGTGTACTTGGACAATCAAAAAGAGTTGATTTTTGTGGAAAGGGCTATCATCTTATGTCCTTCCCTCAGTCAGCACCTCATGGTGTAGTCTTCTTGCATGTGACTTATGTCCCTGCACAAGAAAAGAACTTCACAACTGCTCCTGCCATTTGTCATGATGGAAAAGCACACTTTCCTCGTGAAGGTGTCTTTGTTTCAAATGGCACACACTGGTTTGTAACACAAAGGAATTTTTATGAACCACAAATCATTACTACAGACAACACATTTGTGTCTGGTAACTGTGATGTTGTAATAGGAATTGTCAACAACACAGTTTATGATCCTTTGCAACCTGAATTAGACTCATTCAAGGAGGAGTTAGATAAATATTTTAAGAATCATACATCACCAGATGTTGATTTAGGTGACATCTCTGGCATTAATGCTTCAGTTGTAAACATTCAAAAAGAAATTGACCGCCTCAATGAGGTTGCCAAGAATTTAAATGAATCTCTCATCGATCTCCAAGAACTTGGAAAGTATGAGCAGTATATAAAATGGCCATGGTACATTTGGCTAGGTTTTATAGCTGGCTTGATTGCCATAGTAATGGTGACAATTATGCTTTGCTGTATGACCAGTTGCTGTAGTTGTCTCAAGGGCTGTTGTTCTTGTGGATCCTGCTGCAAATTTGATGAAGACGACTCTGAGCCAGTGCTCAAAGGAGTCAAATTACATTACACATAAACGAACTTATGGATTTGTTTATGAGAATCTTCACAATTGGAACTGTAACTTTGAAGCAAGGTGAAATCAAGGATGCTACTCCTTCAGATTTTGTTCGCGCTACTGCAACGATACCGATACAAGCCTCACTCCCTTTCGGATGGCTTATTGTTGGCGTTGCACTTCTTGCTGTTTTTCAGAGCGCTTCCAAAATCATAACCCTCAAAAAGAGATGGCAACTAGCACTCTCCAAGGGTGTTCACTTTGTTTGCAACTTGCTGTTGTTGTTTGTAACAGTTTACTCACACCTTTTGCTCGTTGCTGCTGGCCTTGAAGCCCCTTTTCTCTATCTTTATGCTTTAGTCTACTTCTTGCAGAGTATAAACTTTGTAAGAATAATAATGAGGCTTTGGCTTTGCTGGAAATGCCGTTCCAAAAACCCATTACTTTATGATGCCAACTATTTTCTTTGCTGGCATACTAATTGTTACGACTATTGTATACCTTACAATAGTGTAACTTCTTCAATTGTCATTACTTCAGGTGATGGCACAACAAGTCCTATTTCTGAACATGACTACCAGATTGGTGGTTATACTGAAAAATGGGAATCTGGAGTAAAAGACTGTGTTGTATTACACAGTTACTTCACTTCAGACTATTACCAGCTGTACTCAACTCAATTGAGTACAGACACTGGTGTTGAACATGTTACCTTCTTCATCTACAATAAAATTGTTGATGAGCCTGAAGAACATGTCCAAATTCACACAATCGACGGTTCATCCGGAGTTGTTAATCCAGTAATGGAACCAATTTATGATGAACCGACGACGACTACTAGCGTGCCTTTGTAAGCACAAGCTGATGAGTACGAACTTATGTACTCATTCGTTTCGGAAGAGACAGGTACGTTAATAGTTAATAGCGTACTTCTTTTTCTTGCTTTCGTGGTATTCTTGCTAGTTACACTAGCCATCCTTACTGCGCTTCGATTGTGTGCGTACTGCTGCAATATTGTTAACGTGAGTCTTGTAAAACCTTCTTTTTACGTTTACTCTCGTGTTAAAAATCTGAATTCTTCTAGAGTTCCTGATCTTCTGGTCTAAACGAACTAAATATTATATTAGTTTTTCTGTTTGGAACTTTAATTTTAGCCATGGCAGATTCCAACGGTACTATTACCGTTGAAGAGCTTAAAAAGCTCCTTGAACAATGGAACCTAGTAATAGGTTTCCTATTCCTTACATGGATTTGTCTTCTACAATTTGCCTATGCCAACAGGAATAGGTTTTTGTATATAATTAAGTTAATTTTCCTCTGGCTGTTATGGCCAGTAACTTTAGCTTGTTTTGTGCTTGCTGCTGTTTACAGAATAAATTGGATCACCGGTGGAATTGCTATCGCAATGGCTTGTCTTGTAGGCTTGATGTGGCTCAGCTACTTCATTGCTTCTTTCAGACTGTTTGCGCGTACGCGTTCCATGTGGTCATTCAATCCAGAAACTAACATTCTTCTCAACGTGCCACTCCATGGCACTATTCTGACCAGACCGCTTCTAGAAAGTGAACTCGTAATCGGAGCTGTGATCCTTCGTGGACATCTTCGTATTGCTGGACACCATCTAGGACGCTGTGACATCAAGGACCTGCCTAAAGAAATCACTGTTGCTACATCACGAACGCTTTCTTATTACAAATTGGGAGCTTCGCAGCGTGTAGCAGGTGACTCAGGTTTTGCTGCATACAGTCGCTACAGGATTGGCAACTATAAATTAAACACAGACCATTCCAGTAGCAGTGACAATATTGCTTTGCTTGTACAGTAAGTGACAACAGATGTTTCATCTCGTTGACTTTCAGGTTACTATAGCAGAGATATTACTAATTATTATGAGGACTTTTAAAGTTTCCATTTGGAATCTTGATTACATCATAAACCTCATAATTAAAAATTTATCTAAGTCACTAACTGAGAATAAATATTCTCAATTAGATGAAGAGCAACCAATGGAGATTGATTAAACGAACATGAAAATTATTCTTTTCTTGGCACTGATAACACTCGCTACTTGTGAGCTTTATCACTACCAAGAGTGTGTTAGAGGTACAACAGTACTTTTAAAAGAACCTTGCTCTTCTGGAACATACGAGGGCAATTCACCATTTCATCCTCTAGCTGATAACAAATTTGCACTGACTTGCTTTAGCACTCAATTTGCTTTTGCTTGTCCTGACGGCGTAAAACACGTCTATCAGTTACGTGCCAGATCAGTTTCACCTAAACTGTTCATCAGACAAGAGGAAGTTCAAGAACTTTACTCTCCAATTTTTCTTATTGTTGCGGCAATAGTGTTTATAACACTTTGCTTCACACTCAAAAGAAAGACAGAATGATTGAACTTTCATTAATTGACTTCTATTTGTGCTTTTTAGCCTTTCTGCTATTCCTTGTTTTAATTATGCTTATTATCTTTTGGTTCTCACTTGAACTGCAAGATCATAATGAAACTTGTCACGCCTAAACGAACATGAAATTTCTTGTTTTCTTAGGAATCATCACAACTGTAGCTGCATTTCACCAAGAATGTAGTTTACAGTCATGTACTCAACATCAACCATATGTAGTTGATGACCCGTGTCCTATTCACTTCTATTCTAAATGGTATATTAGAGTAGGAGCTAGAAAATCAGCACCTTTAATTGAATTGTGCGTGGATGAGGCTGGTTCTAAATCACCCATTCAGTACATCGATATCGGTAATTATACAGTTTCCTGTTTACCTTTTACAATTAATTGCCAGGAACCTAAATTGGGTAGTCTTGTAGTGCGTTGTTCGTTCTATGAAGACTTTTTAGAGTATCATGACGTTCGTGTTGTTTTAGATTTCATCTAAACGAACAAACTAAAATGTCTGATAATGGACCCCAAAATCAGCGAAATGCACCCCGCATTACGTTTGGTGGACCCTCAGATTCAACTGGCAGTAACCAGAATGGAGAACGCAGTGGGGCGCGATCAAAACAACGTCGGCCCCAAGGTTTACCCAATAATACTGCGTCTTGGTTCACCGCTCTCACTCAACATGGCAAGGAAGACCTTAAATTCCCTCGAGGACAAGGCGTTCCAATTAACACCAATAGCAGTCCAGATGACCAAATTGGCTACTACCGAAGAGCTACCAGACGAATTCGTGGTGGTGACGGTAAAATGAAAGATCTCAGTCCAAGATGGTATTTCTACTACCTAGGAACTGGGCCAGAAGCTGGACTTCCCTATGGTGCTAACAAAGACGGCATCATATGGGTTGCAACTGAGGGAGCCTTGAATACACCAAAAGATCACATTGGCACCCGCAATCCTGCTAACAATGCTGCAATCGTGCTACAACTTCCTCAAGGAACAACATTGCCAAAAGGCTTCTACGCAGAAGGGAGCAGAGGCGGCAGTCAAGCCTCTTCTCGTTCCTCATCACGTAGTCGCAACAGTTCAAGAAATTCAACTCCAGGCAGCAGTAGGGGAACTTCTCCTGCTAGAATGGCTGGCAATGGCGGTGATGCTGCTCTTGCTTTGCTGCTGCTTGACAGATTGAACCAGCTTGAGAGCAAAATGTCTGGTAAAGGCCAACAACAACAAGGCCAAACTGTCACTAAGAAATCTGCTGCTGAGGCTTCTAAGAAGCCTCGGCAAAAACGTACTGCCACTAAAGCATACAATGTAACACAAGCTTTCGGCAGACGTGGTCCAGAACAAACCCAAGGAAATTTTGGGGACCAGGAACTAATCAGACAAGGAACTGATTACAAACATTGGCCGCAAATTGCACAATTTGCCCCCAGCGCTTCAGCGTTCTTCGGAATGTCGCGCATTGGCATGGAAGTCACACCTTCGGGAACGTGGTTGACCTACACAGGTGCCATCAAATTGGATGACAAAGATCCAAATTTCAAAGATCAAGTCATTTTGCTGAATAAGCATATTGACGCATACAAAACATTCCCACCAACAGAGCCTAAAAAGGACAAAAAGAAGAAGGCTGATGAAACTCAAGCCTTACCGCAGAGACAGAAGAAACAGCAAACTGTGACTCTTCTTCCTGCTGCAGATTTGGATGATTTCTCCAAACAATTGCAACAATCCATGAGCAGTGCTGACTCAACTCAGGCCTAAACTCATGCAGACCACACAAGGCAGATGGGCTATATAAACGTTTTCGCTTTTCCGTTTACGATATATAGTCTACTCTTGTGCAGAATGAATTCTCGTAACTACATAGCACAAGTAGATGTAGTTAACTTTAATCTCACATAGCAATCTTTAATCAGTGTGTAACATTAGGGAGGACTTGAAAGAGCCACCACATTTTCACCGAGGCCACGCGGAGTACGATCGAGTGTACAGTGAACAATGCTAGGGAGAGCTGCCTATATGGAAGAGCCCTAATGTGTAAAATTAATTTTAGTAGTGCTATCCCCATGTGATTTTAATAGCTTCTTAGGAGAATGACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA"}}